Browsing Auburn Theses and Dissertations by Title
Now showing items 6461-6480 of 8987
PFogSim: A Simulator for Evaluating Dynamic and Layered Fog Computing Environments
(2019-04-24)
The first phase of 5G specification, Release-15, will be completed by April 2019, and our world will truly enter the 5G era. With the advent of 5G, the data transmission cost is expected to reduce significantly. Thus, it ...
PGE mineralization at the Allard stock: Implications for the porphyry to epithermal transition, La Plata Mountains, Colorado
(2014-06-06)
Geochemical and petrographic studies on the Allard stock, which hosts a porphyry Cu-Ag-Au-Te-PGE deposit in the La Plata Mountains of southwestern Colorado, suggest mantle sources for both metals and sulfur. Microprobe ...
Phage at the Air Liquid Interface for the Fabrication of Biosensors
(2005-12-15)
Food borne diseases cause an estimated 76 million illnesses, accounting for 325,000 hospitalizations and more than 5000 deaths in the United States each year. Currently, there are more than 250 known food borne diseases ...
The Phage Behind the Curtain: Determining the Role of Bacteriophage in the Restructuring of Microbiomes During Disease
(2021-11-30)
The gut microbiome is a dynamic microbial ecosystem inhabited by all domains of life and is essential for the homeostatic function of almost all organ systems within the host. Additionally, the mammalian intestine is home ...
Phage-Based Magnetoelastic Sensor for the Detection of Salmonella typhimurium
(2008-12-15)
In recent years, food-borne illness have garnered the attention of mainstream America with calls now coming from the media for more inspections to ensure the safety of our food supply. Food borne illness from the ingestion ...
Phage-coupled Piezoelectric Biodetector for Salmonella typhimurium
(2005-08-15)
Salmonella typhimurium is a leading cause of foodborne illness and a critical threat agent for potential bioterrorism. Current rapid detection initiatives include biosensors that routinely incorporate antibodies for ...
Phage-GnRH Constructs for Population Control of Feral Animals: Evaluation in Cats
(2018-11-15)
The overpopulation of cats is a problem in the United States and worldwide due to public health concerns and their role as a predator of wildlife species. The focus of this research is the development of anti-fertility ...
Pharmacodynamic Effects of Pioglitazone on High Molecular Weight Adiponectin Concentrations and Insulin Response after Oral Sugar in Equids
(2019-07-10)
Chronic insulin dysregulation is challenging to manage with pharmaceuticals in horses. Pioglitazone improves insulin sensitivity in humans, and the pharmacokinetics of pioglitazone have been evaluated in horses. The ...
Pharmacokinetic Modeling for In Vitro/In Vivo Transdermal Absorption
(2017-11-29)
The objective was to determine if a linear pharmacokinetic model could be developed to describe in vitro and in vivo transdermal absorption across normal and microporated skin. Such a model would enable formulators to ...
Pharmacokinetics and Pharmacodynamics of Enrofloxacin and Low-dose Amikacin after Regional Intravenous Limb Perfusion in Standing Horses
(2006-08-15)
Objective - To evaluate the tisular pharmacokinetics/dynamics of enrofloxacin and low-dose amikacin after regional intravenous limb perfusion (RILP) in standing horses.
Animals – Fourteen adult horses
Procedures – ...
Pharmacokinetics of Amikacin after a Single Intravenous Dose
(2009-08-03)
Amikacin, an aminoglycoside antibiotic, has been used extensively in humans and other animals to treat infections produced by Gram-negative bacteria. The pharmacokinetics of amikacin has been studied in foals, but because ...
Pharmacokinetics of intraperitoneal infusion of lidocaine in horses
(2012-07-31)
The objective of this study was to describe the pharmacokinetics of intraperitoneal (IP) lidocaine in horses (30mg/kg). The study was designed as double blinded cross-over, placebo controlled clinical trial, with a 2 weeks ...
Pharmacokinetics of ketamine and lidocaine in serum and milk of mature Holstein cows.
(2006-12-15)
Ketamine and lidocaine are two commonly used anesthetics in veterinary medicine, with some animals occasionally being sent for slaughter following drug administration. The United States Department of Agriculture (USDA) ...
Pharmacokinetics of pimobendan and its metabolite o-desmethyl-pimobendan following rectal administration to healthy dogs
(2020-06-29)
Pimobendan, a benzimidazole-pyridazinone derivative, is an inodilator that is used for the treatment of congestive heart failure in dogs. Pharmacokinetics of pimobendan and its active metabolite o-desmethyl pimobendan ...
Pharmacokinetics of Voriconazole in Horses and Alpacas
(2008-05-15)
Voriconazole is a new antifungal drug that has shown effectiveness in treating serious fungal infections and has the potential for being used in large animal veterinary medicine. The objectives of this study were to ...
Pharmacological characterization and functional rescue of human melanocortin-4 receptor mutants
(2014-07-11)
The melanocortin-4 receptor (MC4R) plays an important role in regulating food intake
and energy expenditure. Previous studies reported that the transmembrane domain 6 was
important in activating several G protein-coupled ...
Pharmacological characterization and functional rescue of the giant panda and human melanocortin-4 receptors
(2017-07-25)
The melanocortin-4 receptor (MC4R) is a member of family A rhodopsin-like G protein-coupled receptors. It is well established that MC4R is critically involved in regulating food intake and energy expenditure in mammals. ...
Pharmacological Characterization of Canine Melanocortin-4 Receptor and Its Natural Variant V213F
(2009-08-03)
Obesity is becoming one of the most significant public health problems all over the world, especially in some developed countries. During the past decade, genetic factors associated with obesity have gained more attention. ...
Pharmacological characterization of fish melanocortin-4 and melanocortin-5 receptors
(2021-07-12)
The melanocortin-4 receptor (MC4R) plays an important role in the regulation of food intake and energy expenditure. The melanocortin-5 receptor (MC5R) has been implicated in the regulation of exocrine gland secretion, ...
Pharmacological regulation of melanocortin-3 and -4 receptors by melanocortin-2 receptor accessory protein 1 or 2
(2022-07-25)
The neural melanocortin receptors (MCRs), melanocortin-3 and -4 receptors (MC3R and MC4R), play essential non-redundant roles in the regulation of energy homeostasis. Melanocortin-2 receptor accessory proteins (MRAPs, MRAP1 ...