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The Development of a Nucleic Acid-Directed Switch and Proximity Dependent Protein Assays using Electrochemical Techniques
The analysis of nucleic acids (NA), has increased demand for point-of-care systems, such as rapid preventive health care, forensic applications, etc. Thus inspired, a vast amount of biosensor platforms for the detection ...
Towards a Bistable Nucleic Acid-Directed Switch for Electrochemical Readout of Proximity Ligation Assays
The work presented in this thesis is focused on the development of a bistable DNA-driven assay formatted for biosensor applications in biological research, medical research, and an approach to point-of-care testing. We ...