Search
Now showing items 1-10 of 13
Determination of Safe and Effective Dosing Regimens for Nonsteroidal Anti-inflammatory Drugs in African and Asian Elephants.
(2019-07-29)
Arthritis and foot disease are well documented conditions affecting captive elephants that are frequently treated with nonsteroidal anti-inflammatory drugs (NSAIDs). An important consideration regarding efficacy and safety ...
Pharmacodynamic Effects of Pioglitazone on High Molecular Weight Adiponectin Concentrations and Insulin Response after Oral Sugar in Equids
(2019-07-10)
Chronic insulin dysregulation is challenging to manage with pharmaceuticals in horses. Pioglitazone improves insulin sensitivity in humans, and the pharmacokinetics of pioglitazone have been evaluated in horses. The ...
Novel Infectious Bronchitis Virus Vaccines and Immune Responses
(2019-11-25)
Infectious bronchitis virus (IBV) occurs as multiple serotypes and genotypes worldwide. In the United States IBV belonging to the Arkansas (Ark) Delmarva Poultry Industry (DPI) genotype is the most frequently isolated ...
Infectious Bronchitis Virus-Host Interaction: Viral Spike Protein Cell/Tissue Binding Specificity and Immune Responses
(2019-10-03)
The coronavirus avian infectious bronchitis virus (IBV) causes a highly contagious disease in chickens affecting the respiratory tract and, depending on virus strains, reproductive and urogenital tracts. Strains are ...
Novel Analgesics and the Impact of Route of Administration in the Horse
(2019-12-05)
primary goal of this dissertation was to describe the disposition of novel analgesics and the impact of their administration on the equine patient. In order to support this aim, a novel, non-septic, transient model of ...
Effects of hyperbaric oxygen therapy on inflammatory factors and antioxidant status in dogs after ovariohysterectomy – a pilot study
(2019-07-02)
Hyperbaric oxygen therapy (HBO) is proven to have anti-inflammatory, antioxidant and healing properties in humans and laboratory animals. However, there are relatively few studies about the effects of HBO in companion ...
Beneficial Modulation of the Gut Microbiota Prevents Stress-Induced Adverse Effects
(2019-04-18)
The gut microbiota plays a significant role in maintaining the homeostasis and overall health status of the host. Moreover, it has been shown that heat stress severely alters the stability of the gut microbiota. Thus, ...
Comparison of Inflammatory Cell Populations in Young and Mature Beef Bulls; A Preliminary Study
(2019-04-24)
Bovine venereal diseases, such as Tritrichomonas foetus (T. foetus) infection, can be economically devastating to the cattle industry. Decreases in calf crops due to abortion and infertility, premature culling, and loss ...
Equine Endothelial Colony Forming Cells: In Vitro and In Vivo Analysis
(2019-07-24)
Endothelial colony forming cells (ECFCs) are a subset of the endothelial progenitor cell (EPC). EPCs are found in bone marrow and in peripheral blood samples, and their subset the ECFC can be isolated from these samples ...
Differential Effects of Niacin on Adipose Tissue Inflammation, Hepatic Function, and Gut Microbiota Composition in C57BL/6J and B6129SF2/J Mice
(2019-07-18)
Background. Obesity is associated with adipose tissue inflammation, development of nonalcoholic fatty liver disease (NAFLD) and altered gut microbiota composition. Niacin is beneficial in inhibiting obesity-associated ...