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Analysis of xenoestrogen effects in the male rat gonad
(2021-04-20)
Naturally occurring estrogenic chemicals existing in food such as soybeans and synthetic xenoestrogens, termed Xenoestrogens, contaminating food and water sources have become issues of public health interest. The concern ...
Angiotensin II-Driven Mechanisms of Neuroinflammation in the Maintenance of Hypertension
(2021-04-20)
Hypertension, one of the most prevalent cardiovascular risk factors, exhibits numerous pathophysiologies and is typically attributed to dysregulation of the cardiovascular, renal, and/or central nervous systems (CNS). ...
The Investigation of Multigenerational and Transgenerational Trichloroethylene Toxicity using the Zebrafish (Danio Rerio)
(2021-04-12)
Multigenerational and transgenerational toxicology studies evaluate the persistence of toxicity in progeny of individuals exposed to a toxicant. For many toxicants, non-genetic mechanisms, especially the alteration of the ...
Taxonomic Profiling of the Lumen and Epimural Surface of the Duodenum, Rumen and Ileum Using a Cannulated Bovine Model
(2021-04-16)
The gut microbiome provides important metabolic functions for the host animal. Bacterial dysbiosis as a result of bacterial, viral, and parasitic gastrointestinal infections can adversely affect the metabolism, productivity, ...
Resistance to colistin and carbapenem among Enterobacteriaceae recovered from human and animal sources is associated with multiple genetic mechanisms
(2021-05-14)
Colistin and carbapenem and are important last-resort antimicrobials to treat infections caused by multidrug-resistant Gram-negative bacteria. Understanding the genetic mechanisms conferring resistance to colistin and ...
Protective Efficacy of a Recombinant Newcastle Disease Virus against Infectious Bronchitis
(2021-07-13)
A previous study has reported that Newcastle disease virus (NDV) recombinant LaSota strain (rLS) expressing infectious bronchitis virus (IBV) Arkansas-type (Ark) trimeric spike ectodomain (Se) (rLS/ArkSe) provides suboptimal ...
The effect of different oxygen concentrations on oxidative stress in anesthetized horses
(2021-07-13)
Anesthesia-associated mortality in horses is high when compared with other species, and may be related to development of hypoxemia during recumbency. To overcome this, high fractions of inspired oxygen (FiO2 >95%) are used. ...
Pharmacological characterization of fish melanocortin-4 and melanocortin-5 receptors
(2021-07-12)
The melanocortin-4 receptor (MC4R) plays an important role in the regulation of food intake and energy expenditure. The melanocortin-5 receptor (MC5R) has been implicated in the regulation of exocrine gland secretion, ...
Biomechanical Testing of Double Hemitenotomy for Equine Deep Digital Flexor Tendon Lengthening
(2021-07-14)
Deep digital flexor (DDF) tenotomy is performed in horses with laminitis to diminish the
force of the DDF on the third phalanx (P3) which causes P3 rotation due to loss of laminar
integrity counteracting the DDF pull. ...
Evaluation of orally and rectally administered misoprostol in a low-dose endotoxin challenge in horses
(2021-07-21)
Endotoxemia occurs in many equine diseases, resulting in systemic inflammatory response syndrome (SIRS). Misoprostol demonstrates in vitro reductions in pro-inflammatory cytokine production when stimulated by endotoxin. ...