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Detection of Tritrichomonas foetus in the Bull
(2023-04-26)
Bovine trichomoniasis is a venereal disease in cattle that causes severe reproductive loss and can have devastating economic impact on the cattle industry. Bovine trichomoniasis is caused by a protozoal organism that ...
Exploring Novel Influenza Vaccine Strategies in the Swine Model: Along With New Potential Come New Challenges
(2023-04-27)
Influenza A virus (IAV) is a highly contagious respiratory pathogen that constitutes a significant threat to global public and animal health. Unremitting antigenic variation of IAV strains not only results in immune evasion ...
Fibroblast Growth Factor-21 (FGF21) in Domestic Cats
(2023-04-26)
Fibroblast growth factors (FGFs) are a group of structurally homologous yet functionally pleiotropic proteins. Unlike canonical and intracellular FGFs, the FGF19 subfamily, which includes FGF15/19, FGF21, and FGF23, act ...
Evaluation of Aerobic Culture Results and the Expression of Embryonic Transcripts From In Vivo Derived Embryos Exposed to Media With and Without Antibiotics
(2023-05-31)
More than 2.8 million antibiotic-resistant infections occur in the United States each year, with a resultant 35,000 deaths. The United States Department of Agriculture is investigating ways to judiciously use antibiotics ...
Multi-dose misoprostol pharmacokinetics and its effect on the fecal microbiome in healthy, adult horses
(2023-07-17)
Misoprostol, a synthetic prostaglandin E1 (PGE1) analogue, is administered to treat glandular gastric ulcers in horses and may possess anti-inflammatory properties. However, misoprostol’s multi-dose pharmacokinetics and ...
Novel Approaches to the Molecular Characterization of Primary Canine Osteosarcoma
(2023-07-24)
Osteosarcoma (OSA) is an aggressive malignant bone tumor that often affects pediatric humans as well as dogs. Canine OSA shares many similarities with the human condition, including clinical presentation and molecular ...
Navigating the Complexities of Disease Prevention, Alternative Treatments, and Multi-Drug Resistant Rhodococcus equi Mitigation Strategies
(2023-07-28)
The opportunistic pathogen, Rhodococcus equi, is a robust soil saprophyte present in the environment of horse-breeding farms and an important cause of pulmonary disease in foals at endemic farms. As an effort to prevent ...
Equine Endothelial Colony-Forming Cells: Phenotypic Enhancement and Ex vivo Angiogenesis Studies
(2023-07-27)
Ischemic diseases in horses are common and often life-threatening, thus cell-based therapies to improve angiogenesis are gaining interest. Endothelial colony-forming cells (ECFCs) can form de novo blood vessels in areas ...
Investigation of gene expression and allelic imbalance in a laboratory marsupial model
(2023-07-27)
Biallelic expression of genes in diploid organisms serves as a crucial mechanism to ensure functional redundancy in case of mutation or loss of one allele. However, exceptions to this rule exist, primarily in genes involved ...
Evaluation of passive immunity and different vaccination protocols on the induction of local and systemic antibody responses and clinical protection of beef calves against experimental infection with bovine respiratory syncytial virus (BRSV)
(2023-07-24)
Bovine respiratory syncytial virus (BRSV) is one of the most prevalent viruses associated with the bovine respiratory disease complex (BRDC). The persistency over time and role of local and systemic antibodies against BRSV ...