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Enantioselective synthesis of 1,6-dihydropyridines with application to natural product synthesis; Racemic total synthesis of the non-nitrogenous opioid collybolide
(2023-08-07)
Azaheterocycles, a common feature of many bioactive natural products, are still challenging motifs to construct in an asymmetric fashion. Dihydropyridines are advantageous intermediates in the synthesis of such heterocycles, ...
Enantioselective synthesis of 1,6-dihydropyridines with application to natural product synthesis; Racemic total synthesis of the fungal metabolite collybolide
(2023-08-09)
Azaheterocycles, a common feature of many bioactive natural products, are still challenging motifs to construct in an asymmetric fashion. Dihydropyridines are advantageous intermediates in the synthesis of such heterocycles, ...
Investigation of Advisor-Advisee Conflict Communication in U.S. Chemistry Graduate Education
(2023-11-28)
The central component of a chemistry Ph.D. program is the research group, where advisors have significant impact on students’ professional development and career path. Current literature indicates that communication issues ...
Synthesis of Cyclobutane-Containing Natural Products using Macrocyclic 1,4-Diketones as Templates for Diastereoselective Transformations and Strained Carbon-Carbon Bond Formation, and the Development of Novel Non-Phosphate Carbohydrate-Based Inhibitors of the IspH-Enzyme in Isoprene Synthesis
(2023-11-27)
Chapter 1: Macrocyclic control as a tool for diastereoselective transformation has been an area of research dating back to Still’s total synthesis of periplanone B. The exact source of this control is not always well ...