Skip to Navigation
Auburn University Homepage
A-Z Index | Map | People Finder
Auburn University Logo
Electronic Theses and Dissertations
Skip to Main Content
Main Navigation 
  • AUETD Home
  • Graduate School
JavaScript is disabled for your browser. Some features of this site may not work without it.
View Item 
  •   AUETD Home
  • View Item
  •   AUETD Home
  • View Item

Studies on The Synthesis of B-Ring 6-Azasteroids

View/Open
Extracted text (44.41Kb)
GANDIKOTA_JYOTHI_56.pdf (306.6Kb)
Date
2006-08-15
Author
Gandikota, Jyothi
Type of Degree
Thesis
Department
Chemistry and Biochemistry
Metadata
Show full item record
Abstract
Azasteroids, which carry a nitrogen in the C-6 position of the steroid nucleus are still mysterious and very few synthesized, were found to possess antimicrobial and antifungal properties apart from their pharmacodynamic actions. The literature reports for synthesizing these compounds is also very limited. We developed different approaches and modified, streamlined procedures for the synthesis of these compounds. The target molecules had different side chains (R= H, Me, Et) at the 6th position and were synthesized using ozone and other oxidizing agents. The oxidative cleavage of the B-ring was the key step to insert a nitrogen atom.
Files
Name:
GANDIKOTA_JYOTHI_56.pdf.txt  
Size:
44.41Kb
Name:
GANDIKOTA_JYOTHI_56.pdf  
Size:
306.6Kb
URI
http://hdl.handle.net/10415/340

Browse

All of AUETDBy Issue DateAuthor / AdvisorTitlesDepartments

My Account

Login

Auburn University Libraries | 231 Mell Street | Auburn, Alabama 36849 | (334) 844-4500 or (800) 446-0387 |

 

Auburn University |Auburn, Alabama 36849 |(334) 844-4000 |

Website Feedback |Privacy |Copyright ©