The Mangalica Pig is a Novel Biomedical Model for Human Obesity and its Metabolic Complications
Metadata Field | Value | Language |
---|---|---|
dc.contributor.advisor | Brandebourg, Terry | en_US |
dc.contributor.author | Roberts, Morgan | en_US |
dc.date.accessioned | 2015-05-29T13:12:30Z | |
dc.date.available | 2015-05-29T13:12:30Z | |
dc.date.issued | 2015-05-29 | |
dc.identifier.uri | http://hdl.handle.net/10415/4663 | |
dc.description.abstract | The Mangalica pig is a genetic model of excessive adiposity; therefore, this European heritage breed may serve as an applied model to improve pork quality in modern commercial lean breeds and as a biomedical model to study obesity-related disease in humans. First growth performance and phenotypic differences were compared between Mangalica breeds and the Yorkshire. Red Mangalica pigs exhibited the most intramuscular fat; moreover, the York x Red Mangalica progeny displayed significantly increased marbling score and lower cook loss compared to the purebred Yorkshire, suggesting Mangalica pigs exhibit superior meat quality and Red Mangalica could serve as a model for studying marbling. Since Mangalica pigs displayed an obese phenotype that was driven by excessive voluntary energy intake, the second study aimed to establish the Mangalica pig as a model for obesity-induced metabolic syndrome. Mangalica pigs spontaneously developed risk factors associated with metabolic syndrome: obesity, hyperglycemia, hyperinsulinemia, dyslipidemia, and low-grade chronic inflammation. Together, these data suggest the Mangalica pig represents a model that enhances biomedical and meat science research. | en_US |
dc.rights | EMBARGO_NOT_AUBURN | en_US |
dc.subject | Animal Sciences | en_US |
dc.title | The Mangalica Pig is a Novel Biomedical Model for Human Obesity and its Metabolic Complications | en_US |
dc.type | Master's Thesis | en_US |
dc.embargo.length | MONTHS_WITHHELD:49 | en_US |
dc.embargo.status | EMBARGOED | en_US |
dc.embargo.enddate | 2019-05-31 | en_US |
dc.contributor.committee | Maxwell, Herris | en_US |
dc.contributor.committee | Rodning, Soren | en_US |