Effect of Omega 3, 6 and 9 Fatty Acids and Vitamin E on Canine Semen Concentration, Motility, Morphology and Cryopreservation
Metadata Field | Value | Language |
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dc.contributor.advisor | Wilborn, Robyn | |
dc.contributor.author | Barstow, Carla | |
dc.date.accessioned | 2018-07-20T15:43:44Z | |
dc.date.available | 2018-07-20T15:43:44Z | |
dc.date.issued | 2018-07-20 | |
dc.identifier.uri | http://hdl.handle.net/10415/6312 | |
dc.description.abstract | There are few studies in dogs investigating the efficacy of male fertility supplements, most notably fatty acids. The objective of this study was to investigate the effects of a commercial fatty acid supplement (OM3 Gold 1000; Spectrum Veterinary; Phoenix, Arizona), on canine semen quality parameters and cryopreservation survivability. Each capsule contained 144 mg linoleic acid, 500 mg alpha-linolenic acid, 203 mg oleic acid and 20 IU vitamin E. Dogs were assigned to either the treatment (n=8) or control group (n=4). All treatment dogs received one capsule of the supplement twice daily for 8 weeks. Ejaculates were collected prior to initiation of treatment then every two weeks for 8 weeks. Ejaculates were cryopreserved at time zero and 8 weeks and post-thaw motility was assessed. The treatment group was then further subdivided into normal dogs (n=4) and sub-fertile dogs (n=4) based upon initial post thaw motilities being greater or less than 30%, respectively. After 8 weeks, sub-fertile treated dogs had an average post thaw motility that increased from 19% to 51% (P = 0.043). Average post thaw motility for normal treated dogs changed from 52% to 58% (P = 0.55) and control dogs from 45% to 53% (P = 0.51). Fatty acid analysis via gas chromatography was performed on the serum and frozen thawed semen initially and 8 weeks after treatment. In all treatment dogs, there was a decrease of omega-6 linoleic acid (P = 0.013) in the serum compared to controls. No change was detected in fatty acid concentrations in frozen thawed semen samples. In summary, supplementation with a fatty acid supplement may help improve post-thaw motility and decrease the concentration of pro-inflammatory omega-6 fatty acids. | en_US |
dc.subject | General Veterinary Medicine | en_US |
dc.title | Effect of Omega 3, 6 and 9 Fatty Acids and Vitamin E on Canine Semen Concentration, Motility, Morphology and Cryopreservation | en_US |
dc.type | Master's Thesis | en_US |
dc.embargo.status | NOT_EMBARGOED | en_US |