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Browsing by Author "David, Allan"
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Bioconversion of lignocellulose into acetone-butanol-ethanol (ABE): pretreatment, enzymatic hydrolysis and fermentation
Guan, Wenjian (2016-12-09)
Abstract
The objective of the present dissertation is to investigate the bioprocess for the production of acetone-butanol-ethanol (ABE) from lignocellulosic feedstocks via ABE fermentation with solvent-producing ...
Bioinspired Microphysiological Systems for in vitro Elucidation of Prostate Tumorigenic Progression and Application in Pre-clinical Therapeutic Evaluation
Habbit, Nicole (2022-12-05) ETD File Embargoed
Contrary to conventional belief, prostate cancer tumors are not merely uniform clusters of cancerous cells that undergo uncontrollable growth and migrate indiscriminately throughout the body. Instead, the prostatic tumor ...
Conversion of Carbon Dioxide and Biomass for Fuels and Chemicals Precursor through Gasification: Experimental and Modeling Approach
Sadhwani, Narendra (2017-03-13)
Recycling carbon dioxide is of prime importance due to the harmful effects on the atmosphere. Using CO2 for gasification serves a dual purpose i.e. reducing pollution and generating syngas and is beneficial both environmentally ...
Conversion of Lignocellulosic Biomass into Monomeric Sugars and Levulinic Acid: Alkaline Pretreatment, Enzymatic Hydrolysis, and Decrystallization
Pallapolu, Venkata Ramesh (2016-08-05)
The technical feasibility of applying uniform pretreatment conditions across the different switchgrass varieties to achieve similar sugar yields was investigated. Four different types of switchgrass species including, ...
Deep tissue imaging of B16 melanoma in mice by Multispectral Optoacoustic Tomography
Bahauddin, Ammar (2022-06-23) ETD File Embargoed
Melanoma is an aggressive type of skin cancer that can metastasize to draining lymph nodes and distant organs. Early detection of melanoma holds the promise of improved patient outcomes by enabling earlier surgical ...
Design and Optimization of a Continuous Bioreactor for Enhanced Cell Production
Avvari, Rithvija (2022-05-02)
This research investigated a novel continuous bioreactor which can be operated both in batch and chemostat modes. The bioreactor showed significant improvement in cell growth due to addition of a spiroid which increased ...
Evaluation of Nanoparticles for the Treatment of Chronic Neuropathic Pain
Harris, Chelsea (2017-07-27)
Pain is something that will affect every person at some point in his or her lifetime,
and yet chronic severe pain remains an often-undertreated medical condition as the
current treatment protocol remains largely unsuccessful ...
Improving the homogeneity of superparamagnetic nanoparticles and a study of their physicochemical properties
Yeh, Barry (2016-08-05)
Superparamagnetic iron oxide nanoparticles (SPIONs) have enormous potential in biomedical applications, including drug delivery, hyperthermia, and magnetic resonance imaging. However, the broad size distribution of SPIONs ...
Improving the homogeneity of superparamagnetic nanoparticles and a study of their physicochemical properties and applications
Yeh, Barry (2018-04-24)
Superparamagnetic iron oxide nanoparticles (SPIONs) have enormous potential in
biomedical applications, including drug delivery, magnetic hyperthermia treatment (MHT), and
contrast enhancement for magnetic resonance ...
Insight into the Effect of Nanoparticles Physicochemical Properties on Ocular Uptake and Transport
Azadi, Marjan (2022-12-05) ETD File Embargoed
The growing population of people suffering from various eye disease has become a concern
for ophthalmologists and drug delivery scientists. Currently, the majority of marketed ophthalmic
formulations are in the form of ...
Investigation into the Synthesis of Polymeric Core and Shell Nanoparticles for the Controlled Release of Small Hydrophobic Payloads
Hahn, Braden (2023-04-26)
Effective and safe delivery of drugs into the body, where it will provide the maximum benefit to the patient, is the ultimate treatment goal. Factors such as the drug’s bioavailability and pharmacokinetics can lessen ...
Investigation of Multicomponent Transport Phenomena in Nafion 117 and Crosslinked Polyether-based Membranes via In Situ ATR FTIR Spectroscopy
Dobyns, Breanna (2020-07-20)
This dissertation focuses on understanding transport and co-transport behavior for a series of species in dense, hydrated polymer membranes. The rate of solute transport through a membrane, permeability, is a fundamental ...
Matrix Metalloproteinase-Responsive Superparamagnetic Iron Oxide Nanoparticles (SPIONs) to Distinguish Between Aggressive and Indolent Cancer
Anani, Tareq (2018-04-24)
Biomedical imaging modalities play a key role in the detection and accurate characterization of cancer lesions. While anatomical imaging modalities provide essential information about the location and size of a tumor lesion, ...
Melanoma drug discovery: Prioritization of candidate melanoma driver mutations in the ErbB4 receptor tyrosine kinase gene and identification of novel molecules that disrupt ErbB4 signaling
Cullum, Richard (2020-04-02)
BRAF V600E mutations are found in roughly 50% of metastatic melanomas. While these tumors typically initially respond to BRAF and/or MEK inhibitors, they frequently develop resistance to BRAF and/or MEK inhibition. ...
A Multi-Technique Perspective for the Calibration of Metal Dispersion and Oxygen Chemisorption on AgTiO2 Supported Adsorbents
Davis, Zenda (2015-07-23)
Absorption studies were performed in an attempt to gain a better understanding of the discrepancies that exist between the previously reported average crystallite sizes for silver titania adsorbents using oxygen chemisorption ...
Next-Gen Thermal Management for Electronics in Space – Asymmetric Sawtooth and Cavity-Enhanced Nucleation-Driven Transport (ASCENT)
Sridhar, Karthekeyan (2023-08-29) ETD File Embargoed
Nucleate pool boiling in microgravity is characterized by stagnant vapor bubble dynamics, leading to early dryout of the heated surface compared to terrestrial conditions. The Asymmetric Sawtooth and Cavity-Enhanced ...
Photo-assisted Adsorptive Desulfurization of Hydrocarbon Fuels over TiO2 and Ag-TiO2
Sun, Xueni (2016-05-05)
Organic sulfur compounds are one of the most common impurities in crude oil which is widely used as transportation fuels such as gasoline, diesel and jet fuels. Sulfur in liquid hydrocarbon fuels is also considered as one ...
Resource and Service Management for Fog Infrastructure as a Service
Shaik, Shehenaz (2019-07-30) ETD File Embargoed
Cloud computing stops short in its offerings towards deployment of latency-critical and bandwidth-intensive applications. Fog computing is emerging as complementary to cloud computing in realizing the deployment of large-scale ...
Silica-based composite nanoparticles as pH-responsive drug carriers and their application in contact lens drug delivery
Fan, Xin (2017-07-25)
Controlled drug delivery from contact lenses is an attractive method to treat ocular disease, like glaucoma, as it overcomes the deficiencies of traditional eye drops, such as poor patient adherence and low bioavailability. ...
Small Molecules Conjugated Silica Nanoparticles for Dual Targeting of Colon Cancer
Sultana, Nayer (2022-12-05) ETD File Embargoed
Colorectal cancer is categorized as the third most commonly diagnosed cancer and the second main reason for cancer death in the United States. The conventional treatments of colorectal cancer like surgery, chemotherapy and ...