Browsing by Department "Biomedical Sciences"
Now showing items 41-60 of 70
Iron-Regulatory Function of Hepcidin in the Channel Catfish and Western Clawed Frog
(2008-05-15)
Hepcidin, originally identified as a 25 amino acid (aa) antimicrobial peptide made in the liver, is a small peptide hormone that has been shown to be the long-sought regulator of iron metabolism in humans and mice. Although ...
Magnetic Resonance Imaging of Radiation-Induced Thymic Atrophy as a Model for Pathologic Changes in Acute Feline Immunodeficiency Virus Infection
(2008-08-15)
The thymus is a primary lymphoid organ responsible for the production of a diverse repertoire of immunocompetent and self-tolerant T lymphocytes (T cells), vital for proper immune function. T lymphocyte differentiation, ...
Mitochondrial Biology: RNA Import and Xenomitochondrial Compensatory Mechanisms
(2011-05-06)
Deficiencies or alterations in mitochondrial function can cause or exacerbate many human diseases, including metabolic and developmental disorders. The first experiments described herein were conducted to study compensatory ...
Molecular Epidemiology and Genetic Analysis of Staphylococcus species in Companion Animal Medicine
(2012-05-01)
In human medicine, methicillin-resistant Staphylococcus aureus (MRSA) is one of the leading causes of bacterial infections in the United States (191). In veterinary medicine, an increased number of multidrug-resistant ...
Molecular Mechanisms Associated with Canine Cyclic Hematopoiesis
(2008-05-15)
Canine cyclic hematopoiesis (CH) is an autosomal recessive disorder characterized by 12-14 day neutrophil cycles, a diluted coat color, and platelet storage pool disease. Canine CH is caused by a mutation in AP3B1, encoding ...
Mutational analysis and coagulation factor VIII sequence in a colt with hemophilia A
(2013-07-10)
Hemophilia A is an X-linked disorder caused by a deficiency in factor VIII (FVIII). Although foals have been diagnosed based on deficiency in FVIII activity, causative gene mutations have not been identified. The objectives ...
Nonequilibrium Thermodynamics and Fitness Costs Associated with Information Preservation May Explain Longevity Differences between Species
(2016-05-05)
The aging process in most organisms is enormously complex, involving a multitude of integrated molecular pathways that define and modulate the gradual cellular, tissue and system-level changes that evoke the aging phenotype. ...
Phage at the Air Liquid Interface for the Fabrication of Biosensors
(2005-12-15)
Food borne diseases cause an estimated 76 million illnesses, accounting for 325,000 hospitalizations and more than 5000 deaths in the United States each year. Currently, there are more than 250 known food borne diseases ...
Pharmacokinetics and Pharmacodynamics of Enrofloxacin and Low-dose Amikacin after Regional Intravenous Limb Perfusion in Standing Horses
(2006-08-15)
Objective - To evaluate the tisular pharmacokinetics/dynamics of enrofloxacin and low-dose amikacin after regional intravenous limb perfusion (RILP) in standing horses.
Animals – Fourteen adult horses
Procedures – ...
Pharmacokinetics of ketamine and lidocaine in serum and milk of mature Holstein cows.
(2006-12-15)
Ketamine and lidocaine are two commonly used anesthetics in veterinary medicine, with some animals occasionally being sent for slaughter following drug administration. The United States Department of Agriculture (USDA) ...
Polymorphism in chicken immune response genes and resistance to disease
(2007-12-15)
Genetic resistance to a number of viral pathogens has been linked to polymorphisms in genes of the immune system. Among these are the genes of the major histocompatibility complex (MHC) and those induced by the type I ...
The Power of the Written Word
(2010-05-10)
A diagnosis of cancer can catapult a person into a time period dominated by uncertainty and a perceived decrease in quality of life. Literature supports that writing honestly about emotions associated with traumas may ...
PPM1A Phosphatase is Involved in Regulating Pregnane Xenobiotic Receptor Mediated Cytochrome P450 3A4 Gene Expression
(2014-12-10)
The liver is the most important organ of drug metabolism and plays a major role in the detoxification of both endobiotics and xenobiotics. The process of drug metabolism is undertaken in three distinct phases. Cytochromes ...
The Presence of the Hyaluronan Receptor CD44 in the Reproductive Tract of the Mare
(2007-12-15)
Objective - To investigate the presence and localization of the hyaluronan receptor CD44
in the reproductive tract of the mare.
Animals Six adult mares
Procedures - Tissue sections of ovaries, oviducts and uterus were ...
Preserving Biological Materials in Protective Polymers
(2005-12-15)
Acacia gum (AG) is a water soluble natural polymer that has many desirable properties for a vast range of applications including those which are used in pharmaceutical, textile and food industries. In this study, a novel ...
Prevalence of Stocker Calves Persistently Infected with Bovine Viral Diarrhea Virus in the Southeast Determined Using Immunohistochemistry on Skin Biopsies
(2009-05-15)
Bovine viral diarrhea virus (BVDV) is an insidious disease affecting cattle worldwide. It can cause early embryonic death, congenital defects, abortions, respiratory disease, immunosuppression, reproductive failure and may ...
Prevalence of Trichomoniasis in Alabama Beef Bulls
(2006-08-15)
Bovine trichomoniasis is a venereal disease caused by the protozoan Tritrichomonas foetus. Trichomoniasis is a major cause of fetal wastage throughout the world, and it causes substantial economic losses wherever natural ...
Protection from Oxidative Stress in the Cardiac H9c2-Cell Line by the Transcription Factor Nrf2
(2007-08-15)
Cardiovascular disease (CVD) is the leading cause of death in the United States, and its prevalence is increasing in all populations and age groups worldwide (71). In 2002 alone, more than 927,000 Americans died from heart ...
Regulation of adiponectin secretion by endothelin-1 and myosin II
(2007-08-15)
Adiponectin is an adipokine with profound insulin-sensitizing, anti-inflammatory and anti-atherogenic properties. Plasma levels of adiponectin are reduced in insulin resistant states such as obesity, type 2 diabetes and ...
Regulation of Glucose Metabolism in a Hepatic and Muscle Cell Line by Adiponectin
(2005-12-15)
Adiponectin is a 30-kD protein secreted by adipose tissue under normal conditions. Serum adiponectin concentrations are decreased in obesity and type 2 diabetes. AdipoR1 and AdipoR2 are two receptors of adiponectin with ...