- AUETD Home
- Browsing by Author
Browsing by Author "Abbott, Kodye"
Now showing items 1-1 of 1
- Sort by:
- issue date
- submit date
Repurposing FDA Approved Drugs to Antagonize Pregnane X Receptor Mediated Chemoresistance
Abbott, Kodye (2019-12-05) ETD File Embargoed
Human pregnane X receptor (hPXR) is an orphan nuclear receptor that regulates key drug metabolism enzymes (DMEs) and drug-transport proteins (DTPs), including Cytochrome p450 3A4 (CYP3A4) and multidrug resistance protein ...