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Novel mechanism of inhibition of the proteasome by Bruton’s Tyrosine Kinase inhibitors
Akintola, Olasubomi (2023-12-12) ETD File Embargoed
Bruton’s tyrosine kinase (BTK) inhibitor Ibrutinib has been shown to synergize in vitro with proteasome inhibitors (PIs) in reducing the viability of cells derived from B-cell malignancies. This synergy was also observed ...