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Browsing by Author "Arnold, Robert D."
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Clinical Pharmacokinetic Analysis and Modeling of Tranexamic Acid in Dogs
Almoslem, Mohammed (2018-05-30)
Tranexamic Acid (TXA) is an FDA approved drug for hemophilia patients undergoing dental extractions and women experiencing heavy bleeding during menstrual periods. It is also used to stop bleeding and decrease risk of ...
Development of lipid based nanoparticles for melanoma treatment
Chen, Li (2015-02-12)
Melanoma is the most malignant skin cancer with high mortality. Currently, it can be treated multiple ways, such as chemotherapy, immunotherapy and targeted therapy. However, patients under these therapies usually have low ...
Development of Polydopamine Nanotubes into a Multi-Functional Drug Delivery System
Sun, Yuzhe (2021-07-20)
In this study, a template-assisted method for the synthesis of polydopamine nanotubes is developed. By altering the amount ratio between dopamine and template, a robust tubular structure is obtained. This unique process ...
Directed Self-Assembly of Tethered Membranes on Nanoparticles
Kelly, Alexander (2018-04-30)
Nanoparticles have demonstrated success in overcoming many barriers of therapeutic delivery. The advantages of these systems include increased drug loading, an ability to package poorly soluble and/or highly toxic drugs, ...
Elucidating the Cognitive Deficits following Doxorubicin treatment
Alhowail, Ahmad (2014-12-11)
Chemotherapeutic drugs are effective in the treatment of various types of tumors;
however, the optimal clinical effectiveness is limited due to secondary effects including
cognitive impairment, also known as “chemobrain”, ...
Synthesis of Janus Nanoparticles using a Packed Column and their Applications
Hanley, Alan (2018-07-27)
Janus nanoparticles, nanoparticles with two regions of differing properties, have been of
interest to researchers for the last 30 years. Differing surface regions of Janus nanoparticles
allows for self-assembly into ...
Three-dimensional Printing of Drug-eluting Implants and Orodispersible Films
Annaji, Manjusha (2023-09-25) ETD File Embargoed
Three-dimensional (3D) printing is a rapidly emerging additive manufacturing technology utilized to quickly fabricate customized dosage forms with complex geometrical designs. Due to its flexibility in adjusting the dose, ...