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Synthesis of Cyclobutane-Containing Natural Products using Macrocyclic 1,4-Diketones as Templates for Diastereoselective Transformations and Strained Carbon-Carbon Bond Formation, and the Development of Novel Non-Phosphate Carbohydrate-Based Inhibitors of the IspH-Enzyme in Isoprene Synthesis
Barnes, Timothy (2023-11-27) ETD File Embargoed
Chapter 1: Macrocyclic control as a tool for diastereoselective transformation has been an area of research dating back to Still’s total synthesis of periplanone B. The exact source of this control is not always well ...