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Browsing by Author "Bird, Richard Curtis"
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Altered Expression Profiles and Defects in a Group of Cell Cycle Regulators and Tumor Suppressor Genes (INK4) and Evaluation of Comprehensive Expression Profiles of Canine miRNAs in Spontaneous Canine Breast Cancer Models
Lutful Kabir, Farruk Mohammad (2014-12-10)
The cyclin-dependent kinase inhibitors (CKIs) act as powerful cell cycle regulators and endogenous tumor suppressors. Defects in members of the INK4A/B CKI tumor suppressors have been associated with human and canine ...
The Cyclin-Dependent Kinase Inhibitor and Tumor Suppressor Locus p16/INK4A- p14ARF and Regulation of the Transition Into and Out of the Cell Cycle
Agarwal, Payal (2011-12-06)
p16/INK4A/CDKN2A is an important tumor suppressor gene located in the INK4A/ARF locus, which encodes a 16 kDa protein known as p16, and a 14 kDa protein known as p14ARF in humans. p16 arrests cell cycle in early G1 phase ...