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Browsing by Author "Byrne, Mark"

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Developing Nucleic Acid-Based Tools for Precision Medicine 

Whitener, Ricky (2019-07-23)
Nucleic acid aptamers are new therapeutic tools that are growing in use in the bionanotechnology field. Understanding their behavior and engineering their structure is desirable for many applications due to unique advantages ...

Differentiation of Mouse Embryonic Stem Cells Using PEG-Fibrinogen Hydrogel Microspheres 

Chang, Samuel (2012-05-15)
Cardiac disease is the leading cause of death worldwide, and current treatments are either ineffective at significantly prolonging lifespan or are unavailable to the majority of patients in need due to a lack of supply. ...

Extended Release of Macromolecular Comfort Agents from Silicone Hydrogel Contact Lenses 

White, Charles, Jr. (2011-04-26)
Contact lens induced dry eye (CLIDE) affects approximately 80% of contact lens wearers. Extrapolating to the world wide population of 300 million contact lens wearers, there are approximately 200 million wearers who express ...

Multi-Enzyme System for the Rapid Metabolism of Ethanol: Kinetics and Conjugation Within pH-Sensitive Hydrogel 

Eggert, Matthew (2012-05-07)
Biohybrid materials, or materials utilizing biological molecules in their rational design, are prime therapeutic carrier candidates to perform detoxification processes. Specifically, catabolic processing of alcohol is a ...

Tunable Polymersomes: Towards Enzyme Delivery Through the Blood-Brain Barrier 

Kelly, Jessica (2017-04-26)
Delivery of therapeutics to the brain through non-invasive administration is a difficult task due to the blood-brain barrier (BBB), which prevents the transport of 98% of therapeutics. In GM1 gangliosidosis, patients are ...