Browsing by Author "Cobine, Paul"

Wilson disease (WD) is a disease characterized by excessive copper accumulation in the liver and various other organs. In WD copper is absorbed through dietary consumption and not properly excreted from the body. Excessive ...

Hyperaccumulators are plants that take up, transport, and sequester large amounts of an element in their tissues. By doing this, they often achieve tissue concentrations that are toxic to most organisms. In this dissertation, ...

Colorful animal ornaments have been a core research focus of the field of sexual selection in evolutionary biology, and carotenoid-based coloration has been particularly well-studied. Animals as diverse as fish, reptiles, ...

Dendritic cells (DCs) are highly potent cells that link the innate immunity with the adaptive. However, these cell types (and their precursors) are extremely rare in vivo. Considerable work has been done to map the development ...

Reproduction is a highly energetic process requiring both prenatal and postnatal investment for female mammals. Under the disposable soma theory (DST), prenatal investment includes reallocation of resources used to maintain ...

Leigh Syndrome is a neurodegenerative disease that presents with bilateral lesions in the brain. This condition is characterized by progressive loss of mental and movement abilities in which these symptoms start as early ...

Bacterial species belonging to the genus Xanthomonas can infect and cause severe diseases in a wide range of host plants including many economically important crops throughout the world. While the majority of studies ...

Carotenoids are the most common source of yellow, orange and red coloration in birds. However, like other vertebrates, birds cannot synthesize carotenoids de novo. To produce carotenoid-based coloration they must ingest ...