Browsing by Author "David, Allan"

Now showing items 1-20 of 23

Bioconversion of lignocellulose into acetone-butanol-ethanol (ABE): pretreatment, enzymatic hydrolysis and fermentation

Guan, Wenjian (2016-12-09)

Abstract The objective of the present dissertation is to investigate the bioprocess for the production of acetone-butanol-ethanol (ABE) from lignocellulosic feedstocks via ABE fermentation with solvent-producing ...

Bioinspired Microphysiological Systems for in vitro Elucidation of Prostate Tumorigenic Progression and Application in Pre-clinical Therapeutic Evaluation

Habbit, Nicole (2022-12-05) ETD File Embargoed

Contrary to conventional belief, prostate cancer tumors are not merely uniform clusters of cancerous cells that undergo uncontrollable growth and migrate indiscriminately throughout the body. Instead, the prostatic tumor ...

Conversion of Carbon Dioxide and Biomass for Fuels and Chemicals Precursor through Gasification: Experimental and Modeling Approach

Sadhwani, Narendra (2017-03-13)

Recycling carbon dioxide is of prime importance due to the harmful effects on the atmosphere. Using CO2 for gasification serves a dual purpose i.e. reducing pollution and generating syngas and is beneficial both environmentally ...

Conversion of Lignocellulosic Biomass into Monomeric Sugars and Levulinic Acid: Alkaline Pretreatment, Enzymatic Hydrolysis, and Decrystallization

Pallapolu, Venkata Ramesh (2016-08-05)

The technical feasibility of applying uniform pretreatment conditions across the different switchgrass varieties to achieve similar sugar yields was investigated. Four different types of switchgrass species including, ...

Deep tissue imaging of B16 melanoma in mice by Multispectral Optoacoustic Tomography

Bahauddin, Ammar (2022-06-23) ETD File Embargoed

Melanoma is an aggressive type of skin cancer that can metastasize to draining lymph nodes and distant organs. Early detection of melanoma holds the promise of improved patient outcomes by enabling earlier surgical ...

Design and Optimization of a Continuous Bioreactor for Enhanced Cell Production

Avvari, Rithvija (2022-05-02)

This research investigated a novel continuous bioreactor which can be operated both in batch and chemostat modes. The bioreactor showed significant improvement in cell growth due to addition of a spiroid which increased ...

Evaluation of Nanoparticles for the Treatment of Chronic Neuropathic Pain

Harris, Chelsea (2017-07-27)

Pain is something that will affect every person at some point in his or her lifetime, and yet chronic severe pain remains an often-undertreated medical condition as the current treatment protocol remains largely unsuccessful ...

Improving the homogeneity of superparamagnetic nanoparticles and a study of their physicochemical properties

Yeh, Barry (2016-08-05)

Superparamagnetic iron oxide nanoparticles (SPIONs) have enormous potential in biomedical applications, including drug delivery, hyperthermia, and magnetic resonance imaging. However, the broad size distribution of SPIONs ...

Improving the homogeneity of superparamagnetic nanoparticles and a study of their physicochemical properties and applications

Yeh, Barry (2018-04-24)

Superparamagnetic iron oxide nanoparticles (SPIONs) have enormous potential in biomedical applications, including drug delivery, magnetic hyperthermia treatment (MHT), and contrast enhancement for magnetic resonance ...

Insight into the Effect of Nanoparticles Physicochemical Properties on Ocular Uptake and Transport

Azadi, Marjan (2022-12-05) ETD File Embargoed

The growing population of people suffering from various eye disease has become a concern for ophthalmologists and drug delivery scientists. Currently, the majority of marketed ophthalmic formulations are in the form of ...

Investigation into the Synthesis of Polymeric Core and Shell Nanoparticles for the Controlled Release of Small Hydrophobic Payloads

Hahn, Braden (2023-04-26)

Effective and safe delivery of drugs into the body, where it will provide the maximum benefit to the patient, is the ultimate treatment goal. Factors such as the drug’s bioavailability and pharmacokinetics can lessen ...

Investigation of Multicomponent Transport Phenomena in Nafion 117 and Crosslinked Polyether-based Membranes via In Situ ATR FTIR Spectroscopy

Dobyns, Breanna (2020-07-20)

This dissertation focuses on understanding transport and co-transport behavior for a series of species in dense, hydrated polymer membranes. The rate of solute transport through a membrane, permeability, is a fundamental ...

Matrix Metalloproteinase-Responsive Superparamagnetic Iron Oxide Nanoparticles (SPIONs) to Distinguish Between Aggressive and Indolent Cancer

Anani, Tareq (2018-04-24)

Biomedical imaging modalities play a key role in the detection and accurate characterization of cancer lesions. While anatomical imaging modalities provide essential information about the location and size of a tumor lesion, ...

Melanoma drug discovery: Prioritization of candidate melanoma driver mutations in the ErbB4 receptor tyrosine kinase gene and identification of novel molecules that disrupt ErbB4 signaling

Cullum, Richard (2020-04-02)

BRAF V600E mutations are found in roughly 50% of metastatic melanomas. While these tumors typically initially respond to BRAF and/or MEK inhibitors, they frequently develop resistance to BRAF and/or MEK inhibition. ...

A Multi-Technique Perspective for the Calibration of Metal Dispersion and Oxygen Chemisorption on AgTiO2 Supported Adsorbents

Davis, Zenda (2015-07-23)

Absorption studies were performed in an attempt to gain a better understanding of the discrepancies that exist between the previously reported average crystallite sizes for silver titania adsorbents using oxygen chemisorption ...

Next-Gen Thermal Management for Electronics in Space – Asymmetric Sawtooth and Cavity-Enhanced Nucleation-Driven Transport (ASCENT)

Sridhar, Karthekeyan (2023-08-29) ETD File Embargoed

Nucleate pool boiling in microgravity is characterized by stagnant vapor bubble dynamics, leading to early dryout of the heated surface compared to terrestrial conditions. The Asymmetric Sawtooth and Cavity-Enhanced ...