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Regioselective Synthesis of Bicyclic Nucleosides and Unsymmetric Tetrasubstituted Pyrene Derivatives with a Strategy for Primary C-2 Alkylation
Dmytrejchuk, Ana (2018-12-03)
CHAPTER 1
The incorporation of synthetic, tricyclic nucleic acid (TriNA) modifications into antisense oligonucleotides (ASOs) with therapeutic applications has been demonstrated to provide increased thermal stability ...