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Mechanisms Underlying Myeloperoxidase Inhibition: Evaluating the Efficacy and Safety of Anti-inflammatory MPO Inhibitors Designed to Limit the Generation of Reactive Oxygen and Nitrogen Species
Huang, Jiansheng (2015-07-24)
Myeloperoxidase (MPO), a heme-containing peroxidase, plays a critical role in the innate immune response by producing hypochlorous acid. MPO-mediated oxidation is also associated with chronic obstructive pulmonary disease ...