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Browsing by Author "Mansour, Mahmoud"
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The Effects of Lactational Exposure to Soy Isoflavones on Testicular Function in the Rat
Napier, India (2011-08-09)
Testosterone, the male androgen responsible for maintaining the male phenotype, is produced by testicular Leydig cells. Leydig cells express estrogen receptors and are therefore regulated by estrogen. Soybeans predominantly ...
Immunohistochemical Localization of the Melanocortin-4 Receptor (MC4R) in the Colon Myenteric Plexus
Parker, Lauren (2010-08-04)
Alpha-melanocyte stimulating hormone (α-MSH) is a tricdecaneuropeptide that can bind four melanocortin receptors (MC1R, MC3R-MC5R) to exert various receptor-dependent effects. MC4R regulates several functions which include ...
PPM1A Phosphatase is Involved in Regulating Pregnane Xenobiotic Receptor Mediated Cytochrome P450 3A4 Gene Expression
Flannery, Patrick (2014-12-10)
The liver is the most important organ of drug metabolism and plays a major role in the detoxification of both endobiotics and xenobiotics. The process of drug metabolism is undertaken in three distinct phases. Cytochromes ...