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Browsing by Author "Mathews, Suresh"
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Altered temporal changes in Ser312-phosphofetuin-A concentrations in response to a glucose challenge in a mouse model of diet-induced obesity and insulin resistance
Okerberg, Carl (2012-07-25)
Recent studies have implicated a role for the liver-secreted glycoprotein fetuin-A in insulin resistance. Fetuin-A negatively regulates insulin action by interacting with the activated insulin receptor and inhibiting ...
A Brief Review of Body Quest: Food of the Warrior, a Childhood Obesity Prevention Initiative, and Impact on Fruit and Vegetable Preference
Smith, Sarah (2013-05-01)
Objective: Body Quest: Food of the Warrior (BQ) was developed as a childhood obesity prevention initiative. This thesis provides a brief program review of BQ and measures the effect of BQ on fruit and vegetable (F/V) ...
Changes in Cardiotrophin-1 and Fibroblast Growth Factor-21 with Weight Loss
Bowers, Robert (2009-11-18)
The purpose of this investigation was to examine the effects of modest weight loss on circulating concentrations of cardiotrophin-1 (CT-1) and fibroblast growth factor-21 (FGF-21) in obese men. Nine obese men (age = 41.5 ...
Effectiveness of a Text Messaging Program to Promote Weight Loss and Improve Dietary Behaviors in Low-income Women Ages 19-49 Years
Griffin, Jamie (2017-04-21)
Combating obesity is a top public health priority in the United States. Currently, Alabama ranks 2nd in the nation for obesity. The goal of this dissertation was to develop My Quest, a 12-week mHealth initiative to evaluate ...
Influence of Dietary Starches Differing in Glycemic Index on Pro-oxidant and Anti-Oxidant Gene Expression and Insulin Sensitivity in a Mouse Model
Colbert, Kathryn (2007-08-15)
The prevalence of obesity and diabetes has reached pandemic proportions worldwide. In the U.S., increased intakes of refined carbohydrates have been reported to parallel this trend. In general, refined carbohydrates (e.g. ...
The Interactive Effects of N-3 Long-Chain Polyunsaturated Fatty Acids and Methylmercury on the Cardiovascular System
Teodorescu, Carmen (2007-12-15)
Coldwater marine fish, an excellent source of n-3 long chain polyunsaturated fatty acids (LCPUFA), is often contaminated with the environmental pollutant methylmercury (MeHg). N-3 LCPUFA and MeHg have contrasting effects ...
Mechanisms Mediating Antidiabetic Effects of Serviceberry extracts, Curcumin, and Stilbenes
Zhang, Jian (2012-05-07)
Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia in which homeostasis of carbohydrate and lipid metabolism is improperly regulated by insulin. Hippocrates (460-377 B.C), said “Let food be ...
Molecular Mechanisms Regulating Hepatic Fetuin-A Expression
Kothari, Vishal (2016-12-05)
Fetuin-A (Fet-A) is a hepatokine, known to inhibit insulin signaling and is associated with diabetes, cardiovascular outcomes and inflammation. Post-translational modification of fetuin-A at different glycosylation and ...
Phosphorylation of fetuin-A, a physiological inhibitor of insulin action, regulated by insulin and leptin
Papizan, James (2007-05-15)
Fetuin-A, a liver secreted phosphoprotein and rat homologue of human a2-HS-glycoprotein (AHSG), is a physiological inhibitor of insulin action. Fetuin-A-null mice exhibit improved glucose tolerance and resistance to weight ...
Plasma Fetuin-A Responses to a Single Bout of Exercise and Short-term Exercise in Obese and Normal Weight Individuals
He, Xiaoming (2010-08-03)
Fetuin-A, in particular the phosphorylated isoform, is a negative regulator of insulin action, inhibiting insulin receptor tyrosine kinase activity and downstream insulin signaling. In obese individuals, serum fetuin-A ...
Ser312 Fetuin-A Phosphorylation and Its Association with Serum Lipids in Metabolic Syndrome
Kaushik, Shalini (2008-08-15)
Fetuin-A (also known as alpha 2-HS-glycoprotein), secreted by the liver into circulation, interacts with the insulin receptor, and is a physiological inhibitor of insulin receptor tyrosine kinase activity in vitro, in ...