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Browsing by Author "Samoylova, Tatiana"

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Exploration Into the Effects of Hypoxia in an In Vitro Canine Glioblastoma Model 

Koehler, Jennifer (2013-04-23)
Glioblastomas are aggressive, lethal primary brain tumors that affect human and canine patients. A subpopulation representing a variably large percentage of the bulk of tumor cells has been identified to have stem cell-like ...

Gonadotropin-releasing Hormone Receptor As A Molecular Target for Contraception in Feral Cats 

Napier, India (2015-12-10)
The global overpopulation of feral cats generates concern regarding their welfare, negative impact on public health, and adverse effects on the environment. In the U.S. and other Westernized countries, the most common ...

Minimally invasive routes of AAV administration to treat GM1 gangliosidosis 

Gross, Amanda (2020-04-17)
GM1 gangliosidosis is a lysosomal storage disease caused by a deficiency of lysosomal β-galactosidase (βgal), which results in the accumulation of GM1 ganglioside and fatal neurodegeneration. In the human type II (late ...

Phage at the Air Liquid Interface for the Fabrication of Biosensors 

Nanduri, Viswaprakash (2005-12-15)
Food borne diseases cause an estimated 76 million illnesses, accounting for 325,000 hospitalizations and more than 5000 deaths in the United States each year. Currently, there are more than 250 known food borne diseases ...

Phage-GnRH Constructs for Population Control of Feral Animals: Evaluation in Cats 

Jones, Rebecca (2018-11-15)
The overpopulation of cats is a problem in the United States and worldwide due to public health concerns and their role as a predator of wildlife species. The focus of this research is the development of anti-fertility ...

Preserving Biological Materials in Protective Polymers 

Krumnow, April (2005-12-15)
Acacia gum (AG) is a water soluble natural polymer that has many desirable properties for a vast range of applications including those which are used in pharmaceutical, textile and food industries. In this study, a novel ...

Tunable Polymersomes: Towards Enzyme Delivery Through the Blood-Brain Barrier 

Kelly, Jessica (2017-04-26)
Delivery of therapeutics to the brain through non-invasive administration is a difficult task due to the blood-brain barrier (BBB), which prevents the transport of 98% of therapeutics. In GM1 gangliosidosis, patients are ...