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Browsing by Author "Sandey, Maninder"

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Association of DNA Copy Number and Structural Variation with Racial Disparities in Childhood Obesity 

Phillips, Megan (2021-04-21)  ETD File Embargoed
Obesity has become a major public health concern throughout the world. Alabama is 6th highest ranked with obesity in the United States. The development of obesity can be influenced by several factors, such as diet, ...

Elucidation of Genomic Structure, Biological Properties, and Functional Status of Canine MDA-7 and Its Receptors 

Sandey, Maninder (2012-05-08)
Human melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24) is a tumor suppressor gene with interleukin properties. Ectopic expression of MDA-7 protein causes growth suppression and induces apoptosis in ...

Fibroblast Growth Factor-21 (FGF21) in Domestic Cats 

Brinker, Emily (2023-04-26)  ETD File Embargoed
Fibroblast growth factors (FGFs) are a group of structurally homologous yet functionally pleiotropic proteins. Unlike canonical and intracellular FGFs, the FGF19 subfamily, which includes FGF15/19, FGF21, and FGF23, act ...

Novel Approaches to the Molecular Characterization of Primary Canine Osteosarcoma 

Nance, Rebecca (2023-07-24)  ETD File Embargoed
Osteosarcoma (OSA) is an aggressive malignant bone tumor that often affects pediatric humans as well as dogs. Canine OSA shares many similarities with the human condition, including clinical presentation and molecular ...

Role of IL-27 in HSV-1-induced Herpetic Stromal Keratitis 

Antony, Ferrin (2024-04-12)  ETD File Embargoed
Herpes Stromal Keratitis (HSK) results from ocular infection with Herpes simplex virus-1 (HSV-1) and is one of the leading causes of infectious blindness. After primary lytic infection in the facial region, the virus ...