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How an Arginine Switch Promotes the Self-preservation of an Hydrogen Peroxide-degrading Enzyme KatG: the Strategic Use of an Active-Site Tryptophan
(2020-07-30)
Catalase-peroxidase (KatG) is a heme-dependent enzyme and an effective H2O2 disposal catalyst, sustaining life for many archaea, bacteria, and lower eukaryotes. Many pathogens employ KatG catalase activity (2 H2O2 -> 2 H2O ...