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Engineered Colorectal Cancer Tissues Employing Patient-derived Cells for Recapitulating the Tumor Microenvironment
(2021-04-21)
Colorectal cancer (CRC) remains the third most prevalent cancer and the third-highest cause of cancer-related deaths among both men and women in the United States. The development of pre-clinical CRC models is vital for ...
Production of Engineered Cardiac Tissue from Encapsulated hiPSCs for Scale-up Studies and Drug-Testing
(2021-04-19)
Cardiovascular disease is the leading cause of death worldwide, causing a global health and financial burden. The first chapter of this dissertation highlights the needs for scalable, clinically relevant production of human ...
Spinel Oxide Hybrid Structures: Designing Battery-like Materials for High-Performance Energy Storage
(2021-04-23)
The electrochemical capacitors, also known as supercapacitors, are the next-generation energy storage devices that can store the energy by a surface or near-surface redox reaction that enables achieving high energy density ...
Valorization of Lignocellulosic Materials - Designing, Synthesis, and Processing of Functional Polymer Nanocomposites
(2021-04-20)
The objective of this research is to valorize lignocellulosic materials obtained from kraft pulp and paper industry for functional applications through design, synthesis, and processing of their nanocomposites. The ...
Establishment of 3D hiPSC cardiac differentiation platforms to investigate congenital heart disease
(2021-04-19)
Cardiac tissue engineering shows great potential for alleviating some of the immense burden of cardiovascular disease. The introduction of human induced pluripotent stem cells (hiPSCs) in 2007 led to a paradigm shift in ...
Surface engineering of conductive material-based composites for energy applications
(2021-07-20)
With the increasing concern on renewable sources (wind, wave and solar), energy storage and power management have become increasingly important topics. Supercapacitors (SCs) with features of ultrahigh power output, excellent ...
Elucidating Interactions within Photoautotroph-Methanotroph Cocultures at Both Systems and Molecular Levels
(2021-07-20)
In the US, the biogas produced from anaerobic digestion (AD) of industrial, municipal, and agricultural waste streams has a great potential as a renewable feedstock. To tap into the immense biogas potential while reducing ...
Microwave-initiated Synthesis of Metal Chalcogenides on Graphene Support for Sustainable Energy Applications
(2021-07-20)
To meet the increasing demand on energy, new types of renewable resources along with advanced energy conversion and storage systems are being developed. Nanotechnology plays a vital role to solve the existing energy issues. ...
Hybrid Machine Learning Techniques for Manufacturing and Beyond
(2021-07-19)
This dissertation presents research performed to develop a novel soft sensor, feature space process monitoring, and domain knowledge-based path analysis for manufacturing and healthcare industries.
In recent years, as ...
Data-Driven Systems Engineering Techniques for Advanced Manufacturing
(2021-07-19)
This dissertation presents research performed in the area of data-driven systems engineering to address some challenges of existing sensing and modeling technologies when applied in the emerging field of advanced manufacturing. ...