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Browsing Auburn Theses and Dissertations by Author "Calderón, Angela"

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Chemical characterization and biological assessment of Euterpe oleracea Mart. (açaí) for in vitro botanical-drug interactions with anticancer drugs 

Heck, Kabre (2024-04-29)  ETD File Embargoed
Cancer is the leading cause of death worldwide, with an estimated 19.3 million new cases in 2020 and almost 10 million cancer deaths. Botanical dietary supplements (BDS) are consumed more by cancer patients than otherwise ...

CYP3A4 inhibition and induction studies coupled to parallel artificial membrane permeability assay (PAMPA) for improved prediction of in-vitro botanical-drug interactions 

Zhang, Yilue (2019-07-10)
The consumption of botanical dietary supplements (BDS) is a common practice among the US population. However, the potential for botanical-drug interactions exists, and their mechanisms have not been thoroughly studied. ...

LC-MS based characterization of Mycobacterium tuberculosis shikimate kinase inhibitors containing oxadiazole-amide and aminobenzothiazole rings 

Alturki, Mansour (2016-07-26)
The emergence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) has increased the demand for the discovery of new antitubercular drugs. The shikimate pathway is essential ...

Rapid Detection and Accurate Discrimination of Microorganisms by Liquid Chromatography, High-Resolution Ion Mobility, and Tandem Mass Spectrometry 

Olajide, Orobola (2024-04-22)
Determining bacterial identity at the strain level is crucial for public health to enable appropriate medical treatment and reduce hospitalization times and antibiotic resistance. To achieve this goal, we have reported the ...