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Investigating the Mechanistic Roles of Conserved Residues in Cysteine Dioxygenase: How a Hydrogen-bonding Network and a Rogue Cysteine Effect L-cysteine Oxidation and Crosslink Formation
Graham, Claire (2019-03-28)
Cysteine Dioxygenase (CDO) catalyzes the oxidation of L-cysteine to L-cysteine sulfinic acid utilizing iron as a cofactor. Adjacent to the iron center is a protein-derived thioether crosslink formed by a cysteine (Cys93) ...