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Now showing items 6135-6154 of 9115
Novel Approaches to Creating Robust Globally Convergent Algorithms for Numerical Optimization
(2009-11-13)
Two optimization algorithms are presented, each of which seeks to effectively combine the desirable characteristics of gradient descent and evolutionary computation into a single robust algorithm. The first method, termed ...
Novel Approaches to the Molecular Characterization of Primary Canine Osteosarcoma
(2023-07-24)
Osteosarcoma (OSA) is an aggressive malignant bone tumor that often affects pediatric humans as well as dogs. Canine OSA shares many similarities with the human condition, including clinical presentation and molecular ...
Novel Bio-Hybrid Nanoscale Carriers Engineered for High Therapeutic Payload and Controllable Extended Release Using Nucleic Acid Aptamers
(2014-05-02)
Controlled delivery of therapeutics to target tissues constitutes a great challenge of modern medicine, especially in the field of cancer treatment where malignant cells have to be killed without damaging the surrounding ...
Novel Catalytic Material with Enhanced Heterogeneous Contacting Efficiency for VOC Removal at Ultra-short Contact Time
(2014-05-02)
Gas processing operations conducted at high velocities (e.g., filtration and catalytic reaction) require specialized media and structure in order to achieve the highest possible level of filtration and/or reaction per unit ...
A novel CPU P-State driver for better thermal control with improved power/performance trade-off
(2015-12-14)
Power consumption and thermal emergencies in multi-core processors are now a major bottleneck due to increased heat dissipation caused by running intensive programs on densely integrated systems. High temperatures lead to ...
Novel Ecology, Novel Activity
(2015-05-05)
Ecosystems are complex, dynamic, and unpredictable to change, evolve, and behave. Change is a normal part of life, and through adaptive and flexible design, we can respond to this complexity. Dynamic ecosystem and novel ...
Novel Enzymes and Catalytic Mechanisms in Tetrapyrrole Metabolism: a Nitrogenase Homolog and a Noncanonical Heme Oxygenase
(2021-07-20)
Methane is the major component of natural gas, which accounts for approximately one quarter of the world’s energy demands. There are many advantages to using methane as a fuel. Methane is an abundance resource. A huge ...
Novel Experimental and Analysis Paradigms for Neuroimaging
(2017-07-25)
Functional magnetic resonance imaging (fMRI) technique uses the blood-oxygen-level-dependent (BOLD) contrast to detect associated changes in blood flow. The BOLD signal is temporal correlated with cerebral electrophysiological ...
Novel experimental technique to confirm fish hosts for “large river mussels”
(2014-07-02)
Unionid mussels are declining in North America. The larval stage (glochidium) represents a life-history bottleneck because glochidia are parasitic and require an appropriate fish host. However, appropriate fish host species ...
Novel Fault Injection Attacks on Logic Locking using ATPG
(2020-07-31)
The outsourcing of the design and manufacturing of integrated circuits (ICs) in the current horizontal semiconductor integration flow includes untrusted entities that have posed various security threats, such as overproduction ...
A novel finite element discretization of domains with spheroidal geometry
(2007-05-15)
We describe and analyze a new finite element discretizations for domains with spheroidal
geometry. In particular, we describe how the method can be used to approximate solutions
as well as eigenvalues and eigenfunctions ...
A Novel Halogenation Protocol and Non-heme Iron Hydroxylase Mimics as Catalysts for C-H Oxidation and O2 Activation
(2012-08-03)
Hydrocarbons react with molar concentrations of peracetic acid and halide salts to yield predominantly monohalogenated products under optimum conditions, with chlorination being more oxidatively efficient than bromination. ...
Novel Hydrogels from Renewable Resources
(2011-05-06)
The cell wall of most plant biomass from forest and agricultural resources consists of three major polymers, cellulose, hemicellulose and lignin. Of these, hemicelluloses have gained increasing attention as sustainable raw ...
Novel Infectious Bronchitis Virus Vaccines and Immune Responses
(2019-11-25)
Infectious bronchitis virus (IBV) occurs as multiple serotypes and genotypes worldwide. In the United States IBV belonging to the Arkansas (Ark) Delmarva Poultry Industry (DPI) genotype is the most frequently isolated ...
Novel Interface Trap Passivation and Channel Counter-doping for 4H-SiC MOSFETs
(2015-05-07)
4H-Silicon carbide (4H-SiC) is the most promising wide band gap semiconductor for next generation high power and high temperature metal-oxide-semiconductor field-effect transistors (MOSFETs). However, the channel mobility ...
Novel Kidney Injury Biomarkers in Young Adults
(2021-08-09)
Chronic kidney disease (CKD) is a condition in which gradual kidney damage impairs its ability to filter blood. CKD has varying levels of severity and tends to become more common, and worsen, with advanced age. If left ...
Novel Lipid Nanoassemblies with Advanced Functionality: Design, Photosynthesis Mimicking and Self-Assembly
(2017-07-31)
Model lipid membranes have attracted considerable attention over the past several decades. They are ideal biomimetic models for studying cells and cellular processes. Due to their unique properties and functional versatility, ...
Novel Machine Learning Algorithms for Analyzing Large-scale Genomic and Genetic Data
(2020-12-01)
With the advancement of next-generation sequencing technology, numerous disease/ phenotypic associations with the human microbiome and human genome are uncovered and revealed. In this dissertation, we take advantage of ...
Novel mechanism of inhibition of the proteasome by Bruton’s Tyrosine Kinase inhibitors
(2023-12-12)
Bruton’s tyrosine kinase (BTK) inhibitor Ibrutinib has been shown to synergize in vitro with proteasome inhibitors (PIs) in reducing the viability of cells derived from B-cell malignancies. This synergy was also observed ...
Novel Metal-Polymer Composite with High Percolation threshold
(2012-04-11)
0-3 metal-polymer composite based on nano-size Ni particles was studied.
A nanocomposite with nano-size Ni particles embedded into copolymer poly [vinylidene fluoride-co-trifluoroethylene] P(VDF-TrFE) 70/30 ...