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P2Y2 Receptor Biased Signaling in Control of Vascular Inflammation 

Lingxin, Zhang (2016-12-09)
Vascular inflammation plays a critical role in the pathogenesis of endotoxic shock and sepsis. Bacterial endotoxins like lipopolysaccharide (LPS) are biologically active substances that initiate the inflammatory response ...

The P2Y2 Receptor Control of Hyperglycemia-induced Insulin Resistance in Human Hepatocytes: A Unified Mechanism for Metformin 

SENFELD, JARED (2022-05-01)  ETD File Embargoed
According to the International Diabetes Federation, in 2021, 537 million adults were living with diabetes, and another 541 million adults were at increased risk of developing T2D (Facts & Figures, 2021.) Obesity, the most ...

Packaging of Silicon Carbide High Temperature, High Power Devices - Processes and Materials 

Liu, Yi (2006-05-15)
Silicon carbide (SiC) has unique electrical, thermal and physical properties compared to the Si and GaAs conventionally used in microelectronics as it can operate in the temperature range from 350ºC to 500ºC. However, there ...

Paired Pulse Basis Functions and Triangular Patch Modeling for the Method of Moments Calculation of Electromagnetic Scattering from Three-Dimensional, Arbitrarily-Shaped Bodies 

Mackenzie, Anne (2008-12-15)
Due to an increasing emphasis on fabrication with composite materials, it is important to be able to model accurately the electromagnetic properties of composite structures. In this work, we demonstrate a new pair of ...

Paleogeographic Reconstruction of Part of Eastern Gondwanaland:Petrofacies and Detrital Geochronologic Study of Permo-Carboniferousgondwanan Sequences of India and Bangladesh 

Chowdhury, Nur Uddin Md. Khaled (2014-08-19)
This study has been carried out focusing on petrofacies and geochronology of Permo-Carboniferous Gondwanan sequences of Barapukuria, Dighipara, and Khalaspir coal basins in the Bengal Basin and Jharia Basin in the Eastern ...

Paleoseismic Investigation of the Relationship of Earthquake-Induced Liquefaction Deposits to Deformation at a Site in the New Madrid Seismic Zone 

Guven, Can (2021-07-28)
Geophysical, geologic, and soil surveys were conducted at a site in the New Madrid seismic zone (NMSZ) to explore the relationship of fluvial sedimentary deposits to earthquake-induced liquefaction features, such as sand ...

Palm Measure Invariance and Exchangeability for Marked Point Processes 

Peng, Man (2008-12-15)
A random measure $\xi$ on a real interval $I$ is known to be exchangeable iff suitably reduced versions of the Palm distributions $Q_{t}$ are independent of $t \in I$. In this dissertation we prove a corresponding result ...

Palmetto Navy: Ironclad Construction and the Naval Defense of Charleston During the Civil War 

Wexler, Charles (2015-05-07)
This dissertation traces the creation and operation of the Charleston Naval Squadron in the Civil War through a look at the different ships and construction strategies implemented within Charleston Harbor. Under the ...

Pannexin 1 Expression in Bovine Cumulus-Oocyte Complexes and Function During in vitro Maturation 

Dye, Zachary (2019-07-03)
In this study we investigate the presence of pannexin 1 (PANX1) protein channels in bovine cumulus-oocyte complexes (COCs). Pannexin channels are a recently discovered family of proteins which have been characterized in ...

Parabolic-Elliptic Chemotaxis Models with Singular Sensitivity 

Kurt, Halil Ibrahim (2022-07-25)  ETD File Embargoed
Chemotaxis describes the movement of biological cells or organisms in response to certain chemicals in their environments and occupies an essential role in coordinating cell movement in many biological circumstances such ...

A Parallel Implementation of Fault Simulation on a Cluster of Workstations 

Han, Kyung (2006-12-15)
Parallel simulation on a cluster workstations is one method by which fault simulation time for large circuits can be reduced significantly. To get near-linear speedups from parallel processing, parallelization methods ...

Parameter Estimation Techniques for Determining Safe Vehicle Speeds in UGVs 

Edwards, Dustin (2008-05-15)
This thesis develops simplified equations to predict a velocity in which vehicle rollover or tire saturation occurs. These equations are functions of different vehicle parameters that are important to vehicle handling ...

Parameters Affecting Bird Use of Stormwater Impoundments in the Southeastern United States: Implications for Bird-Aircraft Collisions 

Fox, Brian James (2011-05-02)
Bird-aircraft collisions are a large and growing threat to aviation safety in the United States. Stormwater management impoundments in and around airports create conditions which attract hazardous wildlife species to air ...

Parameters to Facilitate the Creation of Initial Response Capsules for Survivors of Prodigious Disasters 

McCabe, John (2006-12-15)
The psychological and physiological effect that a catastrophic event has on a person is staggering. Soon after a disaster, many survivors become unruly, hysterical, and in the worse cases even suicidal. After tragedy ...

Parametric Development of Cold Metal Transfer Wire Arc Additive Manufacturing 

Coupland, Conyers (2017-11-20)
Current commercial metal additive manufacturing techniques offer great accuracy and detail in small parts but are characterized by low deposition rates, high cost, and limited scale. This research seeks to develop, review, ...

Parametric Development of Wire 3D Printing 

Gaddes, Jeffrey (2015-12-11)
Currently commercialized additive manufacturing techniques offer great detail in small, difficult to produce parts. They are also slow, limited in scale, and expensive. An additive technique that can rapidly produce large ...

Parametric Study of a Commercial-Scale Biomass Downdraft Gasifier: Experiments and Equilibrium Modeling 

Gautam, Gopal (2010-08-04)
Biomass has already emerged in the renewable energy arena as one of the promising candidates for the future. Biomass has been a major source of fuel for human from the existence of mankind. Rapid urbanization and widespread ...

Paraoxonase Responses to Exercise and Niacin Therapy in Men with Metabolic Syndrome 

Taylor, James (2013-09-12)
Our purpose was to characterize changes in paraoxonase 1 (PON1) activity and concentration after single aerobic exercise sessions conducted before and after 6-weeks of niacin therapy in men with metabolic syndrome (MetS). ...

Parasite component community of Gulf Killifish, Fundulus grandis, in an oiled Louisiana saltmarsh 

Ruiz, Carlos (2013-07-01)
Fish parasites comprise a large portion of marine biodiversity but so far have been underutilized as Gulf of Mexico bioindicators. Shifts in parasite diversity, prevalence, and intensity resulting from the 2010 BP Deepwater ...

A Parasitic Dinoflagellate of the Ctenophore Mnemiosis sp. 

Smith, Khristian (2011-11-14)
In this study I have sought to characterize a previously unknown parasitic dinoflagellate, which is associated with the costal ctenophore Mnemiopsis sp. Here, I describe its general morphology, based on an identification ...