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Modulation of Human PXR by Novel KRAS-G12C Inhibitors: Implications in Cancer Therapy 

Salamat, Julia (2023-08-01)  ETD File Embargoed
The nuclear receptor human pregnane xenobiotic receptor (hPXR) is a transcription factor responsible for the regulation of key drug metabolism enzymes (DMEs) and drug efflux pumps (DEPs), including cytochrome p450 3A4 ...

Moisture and Storage Time Effects on Grinding Characteristics of Loblolly Pine Woodchips 

Oyedeji, Oluwafemi (2015-05-06)
In the processing of biomass to bio-products, grinding is unavoidable. Grinding is used to produce particulate materials and enhance handling, storage, and conversion processes. Performance of grinding operation is usually ...

Moisture Content Monitoring using a Nuclear Moisture Gauge and Preliminary Findings at Alabama Highway 5 

Jones, Dylan (2017-04-20)
Expansive soils cause damage to lightly loaded foundations and structures across the world. Alabama Highway 5 was built directly on an expansive clay soil. In past years it has experienced tremendous amounts of damage ...

Moisture Effects and Viscoelasticity in Polymers Used for Microelectronic Packaging 

Chowdhury, Promod (2019-12-06)  ETD File Embargoed
In the microelectronics packaging industry, polymer based materials are used widely. Reliable, consistent and comprehensive material property data are required for mechanical design, process optimization, and reliability ...

A Molecular and Field Survey Approach to Understanding Legume Viruses in Alabama 

Mayfield, Michael (2021-08-04)
Legumes grown in Alabama contribute to hundreds of millions of dollars for the state’s economy. During the soybean growing season, viruses prevalent in Alabama such as Soybean mosaic virus (SMV), Soybean vein necrosis ...

Molecular and serological diagnosis of Dirofilaria immitis in companion animals, USA 

Barrantes Murillo, Daniel Felipe (2024-04-12)  ETD File Embargoed
Heartworm Disease (HWD) is caused by the nematode Dirofilaria immitis; a zoonotic infectious agent that affects companion animals and is transmitted by mosquito vectors. The diagnosis of HWD can be achieved by the combination ...

A Molecular Approach to Determine the Origin of Fecal Bacteria in the Catoma Creek Watershed 

Wijesinghe, Rasanthi (2005-12-15)
High concentrations of fecal indicator bacteria are the most common cause of surface-water impairment in Alabama. A 37 km segment of Catoma Creek in Montgomery Country has been included on Alabama 303(d) List of impaired ...

Molecular Basis of the Role of Calcium in Xylella fastidiosa Infection Process 

Chen, Hongyu (2019-07-16)
Xylella fastidiosa, a xylem-limited bacterial phytopathogen, is the causal agent of devastating diseases on many economically important plants worldwide. During plant infection, X. fastidiosa modifies the mineral content ...

Molecular Biology and Epidemiology of Human and Feline Coronaviruses 

Barua, Subarna (2022-12-05)
Coronaviruses (CoVs) are RNA viruses belonging to the Coronaviridae family and known to infect various hosts such as pigs (porcine epidemic diarrhea virus), cats (feline infectious peritonitis virus), birds (avian coronavirus), ...

Molecular Bonding in Product Engineering 

Thote, Amol (2005-08-15)
Molecular Bonding plays an important role in the performance of product and chemical processes. Various types of bonds are: ionic bond, covalent bond, co-ordinate bond, metallic bond, van der Waal’s bond and hydrogen bond. ...

Molecular Characterization of Diverse Mechanisms of Mucosal Immunity in Teleost Fishes 

Zhang, Dongdong (2017-11-27)
The mucosal barriers (gill, skin and intestine) of fish constitute the first line of defense against aquatic pathogens invasion. By exploring and targeting fish mucosal immune system, we can rationally design better vaccines ...

Molecular characterization of Edwardsiella spp. and Flavobacterium columnare 

Zhang, Yinfeng (2007-08-15)
Bacterial diseases are responsible for large economic losses in aquaculture around the world. Flavobacterium columnare and Edwardsiella spp. negatively impact the channel catfish industry in southern USA. However, limited ...

Molecular Dynamics Simulations of Dry Sliding Asperities to Study Friction and Frictional Energy Dissipation 

Vadgama, Bhavin N. (2014-03-31)
Fundamental friction characteristics such as the friction coefficient, wear, adhesion, and dissipation of energy require an accurate understanding of how the surfaces in contact interact on nano or atomic scale. At nano ...

Molecular dynamics studies of phase transition of n-alkanes mixtures, coupling-decoupling mechanism affecting thermal interfacial conductance of n-alkanes and Fokker-Planck theory of lattice thermal conductivity of crystalline solids 

Zeng, Yi (2019-12-05)
Renewable energy sources, such as solar energy or geothermal energy, are promising to complement or even substitute unsustainable fossil fuel energy sources in direct thermal energy utilization. The requirement of a reliable ...

Molecular Ecology of Peromyscus polionotus 

Van Zant, Jeffrey L. (2006-08-15)
Lowe et al. (2004) describes ecological genetics as “the investigation of the origin and maintenance of genetic variation within and between populations, which ultimately leads to adaptation and speciation.” Thus, to gain ...

Molecular Epidemiology and Genetic Analysis of Staphylococcus species in Companion Animal Medicine 

Diaz-Campos, Dubraska (2012-05-01)
In human medicine, methicillin-resistant Staphylococcus aureus (MRSA) is one of the leading causes of bacterial infections in the United States (191). In veterinary medicine, an increased number of multidrug-resistant ...

Molecular Evolutionary and Functional Genomic Studies of Marshallia (Asteraceae) Utilizing Next Generation Sequencing Technology 

Melton, Anthony (2015-05-06)
Several aspects of Marshallia (Asteraceae) genomics have been investigated using NGS technologies. I have assembled and characterized Marshallia Clade III Cytokinin Response Factor genes from DNA and RNA datasets. To ...

Molecular Interactions between phage and the catfish pathogen Edwardsiella ictaluri and Comparative Genomics of Epidemic strains of Aeromonas hydrophila 

Hossain, Mohammad (2012-12-05)
Edwardsiella ictaluri causes Enteric Septicemia of Catfish (ESC) which is responsible for significant economic loss of the catfish aquaculture industry in the southeastern United States. A better diagnostic tool is required ...

Molecular Investigations of the Diversity of Freshwater Fishes across Three Continents 

Hayes, Malorie (2020-07-02)
Fishes are the most speciose vertebrates, and incredible diversity can be found within different groups of fish. Due to their physiological limitations, fish are confined to waters, and in freshwater fish, this is restricted ...

Molecular Mechanisms Associated with Canine Cyclic Hematopoiesis 

Meng, Ronghua (2008-05-15)
Canine cyclic hematopoiesis (CH) is an autosomal recessive disorder characterized by 12-14 day neutrophil cycles, a diluted coat color, and platelet storage pool disease. Canine CH is caused by a mutation in AP3B1, encoding ...