Browsing Auburn University Graduate School by Department "General Veterinary Medicine"
Now showing items 1-20 of 103
Adenoviral Vectored Gonadotropin Releasing Hormone Vaccine for Estrus Suppression in Mares
(2017-07-27)
The objective of this study was to evaluate an adenoviral vectored gonadotropin releasing hormone (GnRH) vaccine as a method to suppress estrus behavior and cyclicity in mares. An additional objective was to determine the ...
Airway Deposition of Nebulized Voriconazole in Horses
(2020-11-02)
Voriconazole (VRC) is a potential treatment for pneumomycosis in horses. The objectives of this study were to determine if delivery of Vfend® using a Flexineb® nebulizer produced clinically significant [VRC] in lower ...
Analysis of xenoestrogen effects in the male rat gonad
(2021-04-20)
Naturally occurring estrogenic chemicals existing in food such as soybeans and synthetic xenoestrogens, termed Xenoestrogens, contaminating food and water sources have become issues of public health interest. The concern ...
Angiotensin II-Driven Mechanisms of Neuroinflammation in the Maintenance of Hypertension
(2021-04-20)
Hypertension, one of the most prevalent cardiovascular risk factors, exhibits numerous pathophysiologies and is typically attributed to dysregulation of the cardiovascular, renal, and/or central nervous systems (CNS). ...
Antimicrobial-resistant bacteria and microbiota identified among flies and their sympatric animals
(2020-07-21)
Antimicrobial resistance is rising globally at an alarming rate as one of the most serious public health challenges. There is increasing evidence that the environment plays a major role in the development and transmission ...
Assessment of Breeding Soundness in White-tailed Deer in Alabama
(2022-08-12)
The deer family (Cervidae) has a nearly world-wide distribution, and deer farming has, in recent years, been gradually accepted as an economically promising industry. It is demonstrated that ungulate body size and horn/antler ...
Australian Labradoodle Dystrophinopathy: A Novel Canine Model for the Study of Duchenne Muscular Dystrophy Cardiomyopathy
(2020-04-22)
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder that results in progressive damage to both skeletal and cardiac myocytes. As a result of improved ventilatory care, mortality in affected patients is ...
Bacterial and fungal symbionts in parasitoid wasp genera Nasonia and Muscidifurax
(2023-12-04)
Jewel wasps in the Nasonia genus are ideal models for insect genetics, genomics, epigenetics, development, and evolution. Wasps in the Muscidifurax genus have a close evolutionary relationship to the model parasitoid genus ...
Bacterial and fungal symbionts in parasitoid wasp genera Nasonia and Muscidifurax
(2023-12-04)
Jewel wasps in the genus of Nasonia are ideal models for insect genetics, genomics, epigenetics, development, and evolution. Wasps in the Muscidifurax genus have a close evolutionary relationship to the model parasitoid ...
Beneficial Modulation of the Gut Microbiota Prevents Stress-Induced Adverse Effects
(2019-04-18)
The gut microbiota plays a significant role in maintaining the homeostasis and overall health status of the host. Moreover, it has been shown that heat stress severely alters the stability of the gut microbiota. Thus, ...
A Biodegradable Microparticle Vaccine Platform using Femtomole Peptide Antigen Doses to Elicit T-cell Immunity against Chlamydia abortus
(2016-12-19)
Successful vaccination against Chlamydia spp. has remained elusive, largely due to a lack of vaccine platforms for the required Th1 immunization. Modeling of T helper cell immunity indicates that Th1 immunity requires ...
Biomechanical Testing of Double Hemitenotomy for Equine Deep Digital Flexor Tendon Lengthening
(2021-07-14)
Deep digital flexor (DDF) tenotomy is performed in horses with laminitis to diminish the
force of the DDF on the third phalanx (P3) which causes P3 rotation due to loss of laminar
integrity counteracting the DDF pull. ...
Canine and Feline Differences in the Cytochrome P450 Transcriptome and Drug Metabolism
(2018-04-17)
Cytochrome P450 (CYP) is an important enzyme superfamily, estimated to metabolize 70-90% of pharmaceuticals. Use of pharmaceuticals with at least 30% metabolism by CYP in humans require phenotyping to determine the CYP ...
Cannabinoid: A Potential Anti-Cancer Agent for Non-Hodgkin Lymphoma
(2021-07-23)
The non-Hodgkin lymphomas (NHLs) are a heterogeneous family of lymphoid malignancies and are one of the most commonly diagnosed neoplasm in both dogs and humans. Systemic anticancer chemotherapy is the treatment of choice ...
Cardiac Output Measurements with UDCO and ECHO under general anesthesia during normotension, hypotension and hypertension in adult alpacas
(2021-07-30)
Cardiac output (CO) is defined as the quantity of blood pumped into the aorta each minute by the heart. Measurement of CO is considered an important tool to determine oxygen deliver to the tissues. Currently, there are ...
Changes in the Open Reading Frame of Bovine Viral Diarrhea Virus during Serial Infection of Pregnant Cattle, Sheep, and Swine
(2018-04-24)
Bovine viral diarrhea virus (BVDV) is an economically important pathogen that is endemic in cattle populations of many countries. This virus can also infect pigs, camelids, and a wide range of ruminants including sheep, ...
Characterization and differentiation of bacteria by hyperspectral analysis
(2019-07-19)
Characterization and differentiation of microorganisms by hyperspectral analysis is a promising alternative to conventional techniques in clinical, food, and environmental microbiology to be used as a rapid, non-destructive ...
Characterizing the Gut Microbiota of Obese Cats and Exploring the Association Between Gut Microbiota and Memory in Dogs Using Metagenomic Sequencing
(2024-12-09)
The gut microbiota plays a crucial role in the health and physiology of animals, significantly affecting various biological processes and disease mechanisms. However, there are limited studies on the gut microbiota in cats ...
Clinical Applications of Therapeutic Drug Monitoring in Canine Idiopathic Epilepsy Patients Receiving Levetiracetam
(2018-11-20)
There are currently no drugs approved for the treatment of canine idiopathic epilepsy and as a result extra-label use of human-approved medications is common. Older agents such as phenobarbital are effective in dogs, but ...
Cloning and characterization of novel ccdc103 interactors
(2020-07-16)
Coiled-coil domain containing protein 103 is a homodimeric protein that functions as a dynein attachment factor in motile cilia. Ccdc103 defects in zebrafish (Danio rerio) embryos lead to paralyzed motile cilia, pronephric ...