Browsing Auburn Theses and Dissertations by Department "General Veterinary Medicine"
Now showing items 41-60 of 96
Equine Endothelial Colony-Forming Cells: Phenotypic Enhancement and Ex vivo Angiogenesis Studies
(2023-07-27)
Ischemic diseases in horses are common and often life-threatening, thus cell-based therapies to improve angiogenesis are gaining interest. Endothelial colony-forming cells (ECFCs) can form de novo blood vessels in areas ...
Evaluation of Aerobic Culture Results and the Expression of Embryonic Transcripts From In Vivo Derived Embryos Exposed to Media With and Without Antibiotics
(2023-05-31)
More than 2.8 million antibiotic-resistant infections occur in the United States each year, with a resultant 35,000 deaths. The United States Department of Agriculture is investigating ways to judiciously use antibiotics ...
Evaluation of orally and rectally administered misoprostol in a low-dose endotoxin challenge in horses
(2021-07-21)
Endotoxemia occurs in many equine diseases, resulting in systemic inflammatory response syndrome (SIRS). Misoprostol demonstrates in vitro reductions in pro-inflammatory cytokine production when stimulated by endotoxin. ...
Evaluation of passive immunity and different vaccination protocols on the induction of local and systemic antibody responses and clinical protection of beef calves against experimental infection with bovine respiratory syncytial virus (BRSV)
(2023-07-24)
Bovine respiratory syncytial virus (BRSV) is one of the most prevalent viruses associated with the bovine respiratory disease complex (BRDC). The persistency over time and role of local and systemic antibodies against BRSV ...
Evaluation of the Aberdeen and Forwarder knots in large gauge suture
(2016-07-22)
Methods: Forwarder, Aberdeen, surgeon’s and square knots were tested using large gauge suture under linear tension on a universal testing machine, recording knot holding capacity (KHC). Relative knot security (RKS) was ...
Ex vivo comparison of the bursting strength of surgeon’s knot compared to self-locking knots for closure of ventral midline celiotomy in horses.
(2018-07-27)
It is not uncommon for the equine population to experience abdominal pain referred to as
‘colic’. It is estimated that approximately 9% of the general population of horses that experience
colic require surgical intervention. ...
Exploring Novel Influenza Vaccine Strategies in the Swine Model: Along With New Potential Come New Challenges
(2023-04-27)
Influenza A virus (IAV) is a highly contagious respiratory pathogen that constitutes a significant threat to global public and animal health. Unremitting antigenic variation of IAV strains not only results in immune evasion ...
Fibroblast Growth Factor-21 (FGF21) in Domestic Cats
(2023-04-26)
Fibroblast growth factors (FGFs) are a group of structurally homologous yet functionally pleiotropic proteins. Unlike canonical and intracellular FGFs, the FGF19 subfamily, which includes FGF15/19, FGF21, and FGF23, act ...
Genetic and genomic enhancement of the aquaculture production of hybrid catfish
(2023-08-03)
Channel catfish (Ictalurus punctatus) and blue catfish (Ictalurus furcatus) are two important freshwater aquaculture species in the United States. Interspecific hybridization is an efficient strategy to enhance production ...
Identifying potential modifiers of hereditary breast cancer risk in a large African American family
(2020-11-16)
Next-generation sequencing technology has advanced such that research discoveries can be accelerated. In the area of hereditary breast cancer genetics specifically, known breast cancer susceptibility genes only contribute ...
Improving Reproductive Efficiency and Calving Distribution of Heifers Through Estrus Synchronization, Natural Service, and Fixed-Time Artificial Insemination
(2020-07-13)
Artificial insemination has is considered to be one of the most important innovations in cattle management. Fixed-time artificial insemination (FTAI) protocols have offered new opportunities to implement AI, however, these ...
In vitro anti-tubulin effects of mebendazole and fenbendazole on J3T canine glioma cells
(2016-08-24)
Benzimidazole anthelmintics have reported anti-neoplastic effects both in vitro and in vivo. The purpose of this study was to evaluate the in vitro chemosensitivity of canine glioma J3T cells to mebendazole and ...
In vitro effect of Altered Platelet Count on Multiple Electrode Impedance Aggregometry in Dogs
(2017-01-10)
The objective of this study was to assess platelet aggregation by impedance aggregometry using canine whole blood with adjusted platelet counts. Citrated venous samples from 24 healthy dogs were aliquoted into unmanipulated ...
An In Vitro Study Assessing the Effect of Fluid Media on the Mechanical Properties of Pattern Starting and Ending Surgeon’s, Square and Aberdeen knots
(2017-07-07)
The objective of this study was to investigate the knot holding capacity (KHC) of pattern starting and ending square, surgeon’s and Aberdeen knots each tied in 4 throw combinations using either 2USP polydioxanone or 3USP ...
Infectious Bronchitis Virus-Host Interaction: Viral Spike Protein Cell/Tissue Binding Specificity and Immune Responses
(2019-10-03)
The coronavirus avian infectious bronchitis virus (IBV) causes a highly contagious disease in chickens affecting the respiratory tract and, depending on virus strains, reproductive and urogenital tracts. Strains are ...
Intestinal interactions of Eimeria spp. with Clostridium perfringens and Salmonella Typhimurium in broiler chickens
(2023-08-02)
Coccidia, Clostridium perfringens, and Salmonella are intestinal pathogens in broiler production. Coccidiosis in chickens is caused by Eimeria spp. The infection provides a growth advantage to Clostridium perfringens (CP), ...
Investigating HCAR and FAN1 Variants as Inherited Risk Factors of Breast Cancer
(2022-04-22)
Inherited genetic risk factors in known breast cancer (BC) susceptibility genes
increase an individual’s overall lifetime risk of developing BC but explain only ~35% of
hereditary BC cases. Therefore, additional BC ...
Investigation of gene expression and allelic imbalance in a laboratory marsupial model
(2023-07-27)
Biallelic expression of genes in diploid organisms serves as a crucial mechanism to ensure functional redundancy in case of mutation or loss of one allele. However, exceptions to this rule exist, primarily in genes involved ...
The Investigation of Multigenerational and Transgenerational Trichloroethylene Toxicity using the Zebrafish (Danio Rerio)
(2021-04-12)
Multigenerational and transgenerational toxicology studies evaluate the persistence of toxicity in progeny of individuals exposed to a toxicant. For many toxicants, non-genetic mechanisms, especially the alteration of the ...
Kinetic Effects of Heat Stress on Olfaction: A Thermodynamic Evaluation of Electrical Responses to Odorants in Olfactory Epithelia
(2018-04-23)
Detection dogs are exposed to some of the most extreme environmental conditions in the world while simultaneously expected to maintain maximal olfactory function. Sometimes these conditions exceed their thermoregulatory ...