Browsing Auburn Theses and Dissertations by Department "Chemistry and Biochemistry"

Now showing items 81-100 of 221

The Extension of Colloid Chemistry from Aqueous to Non-Aqueous Media with Application to Nanofluid Research

Clary, Dan (2011-11-17)

Nanofluids are colloids whose design is specific to the study and application of heat transfer systems. Metals typically have thermal conductivities which are several times higher than that of traditional cooling liquids ...

First Principle Studies on Ground and Excited Electronic States: Chemical Bonding in Main-Group Molecules, Molecular Systems with Diffuse Electrons, and Water Activation using Transition Metal Monoxides

Ariyarathna, Isuru (2021-03-01)

Potential energy profiles can be used to investigate the origins of chemical bonding of molecules. Such profiles were adopted to show the propagation of lone pair electrons of N2(X1Σg+) to the vacant orbital of O(1D) or ...

Formation and Passivation of Sub-Nanoliter Droplets for High Throughput Biological Assay Platforms

DeJournette, Cheryl (2014-07-24)

In Vitro Compartmentalization (IVC) is a technique that utilizes water-in-oil emulsion droplets of fL – nL volume to compartmentalize and perform biological reactions and assays in parallel. At its highest capacity it has ...

Functional Genomics Investigation of Siroheme and Heme d1 Biosynthesis

Owens, Victoria (2019-06-12) ETD File Embargoed

Many bacteria and archaea grow under anaerobic or microaerophilic conditions. In order for these organisms to survive under these conditions, many utilize nitrate or nitrite as terminal electron acceptors for anaerobic ...

Functional Roles of Conserved Active Site Amino Acids in the Desulfonation Reaction Catalyzed by the Alkanesulfonate Monooxygenase from Escherichia coli

Carpenter, Russell (2008-12-15)

The flavin-dependent alkanesulfonate monooxygenase (SsuD) catalyzes the oxidation of 1-substituted alkanesulfonates producing sulfite and a corresponding aldehyde in the presence of O2 and FMNH2. The reduced flavin is ...

Gene Duplication and Fusion: Strategy for Active Site Control and Starting Point for New Catalysts

Wang, Yu (2012-12-10)

Catalase–peroxidases (KatGs) have two peroxidase-like domains. The N-terminal domain contains the heme-dependent, bifunctional active site. Though the C-terminal domain lacks the ability to bind heme or directly catalyze ...

Giant Janus Liposomes: Preparation, Self-Assembly and Motion

Liu, Zening (2020-07-17)

Presented in this Dissertation are a series of studies on Janus liposomes, their formation, self-assembly and motion behaviors. Liposomes are closed, spherical lipid bilayer assemblies dispersed in water. Since their ...

How an Arginine Switch Promotes the Self-preservation of an Hydrogen Peroxide-degrading Enzyme KatG: the Strategic Use of an Active-Site Tryptophan

Xu, Hui (2020-07-30)

Catalase-peroxidase (KatG) is a heme-dependent enzyme and an effective H2O2 disposal catalyst, sustaining life for many archaea, bacteria, and lower eukaryotes. Many pathogens employ KatG catalase activity (2 H2O2 -> 2 H2O ...

Human Glutaminase Interacting Protein (GIP): a Potential Candidate for Anti-Cancer Drug Design

Banerjee, Monimoy (2011-08-04)

PDZ domains are one of the most ubiquitous protein-protein interaction modules found in living systems. The glutaminase interacting protein (GIP), also known as the Tax interacting protein 1 (TIP-1), is a PDZ domain ...

Hydrothermal Syntheses, Structures, and Properties of New Iodate and Selenite Compounds of Transition Metals, Lanthanides, and Actinides

Ling, Jie (2007-12-15)

Iodate and selenite anions possessing a nonbonding, but stereochemically active lone pairs of electrons, were selected as building blocks to produce new compounds with noncentrosymmetric structures, a prerequisite for ...

Hydrothermal Synthesis and Characterization of Novel Thorium, Uranium, and Neptunium Solids

Sullens, Tyler (2005-08-15)

Hydrothermal synthesis has been utilized to synthesize several compounds involving thorium, uranium, and neptunium. These compounds have one-, two-, and three-dimensional structural typologies. A majority of the compounds ...

The Identification of Critical Active-Site Groups and Catalytic Steps Governing the Desulfonation Reaction by Alkanesulfonate Monooxygenase

Robbins, John (2012-10-08)

The alkanesulfonate monooxygenase enzyme (SsuD) catalyzes the oxygenolytic cleavage of a carbon-sulfur bond of sulfonated substrates. A mechanism involving acid-base catalysis is proposed for the desulfonation mechanism ...

Identification of Pesticides Using Experimental and Computational Approaches based on Ion Mobility Mass Spectrometry Measurements

Benedicta, Donkor (2022-07-14)

Mass spectrometry is known to be a powerful analytical technique due its high sensitivity, specificity, speed, and versatility. It has the capability of detecting and identifying numerous analytes in sample matrices. In ...

Identifying the Knowledge and Skills that Doctoral Chemists Require in the Workplace

Cui, Qi (2021-04-16) ETD File Embargoed

In 2012, the National Research Council and the American Chemical Society reported many critiques of graduate education in the chemical sciences that do not adequately prepare students for the interdisciplinary careers for ...

Identifying the Role of His293 in Protein Arginine Methyltransferase 1 and Characterization of Agonists for Peroxisomal Proliferator Activating Receptors

Boykin, Brittany (2016-05-04)

This thesis presents two proteins of interest: (1) protein arginine methyltransferase 1 (PRMT1) and (2) peroxisome proliferator activated receptors (PPARs). The purpose of this thesis is to assess the intermolecular ...

Impacts of the oxidizable scaffold of catalase-peroxidase (KatG): Modulation of a heme peroxidase for catalytic versatility

Krewall, Jessica (2021-09-15)

Catalase-peroxidase (KatG) is an antioxidant protein that plays a key role in the degradation of H2O2 for pathogenic and non-pathogenic bacteria and lower eukaryotes. Despite having the general structure of a heme peroxidase, ...