This Is AuburnElectronic Theses and Dissertations

Browsing Auburn Theses and Dissertations by Department "General Veterinary Medicine"

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Adenoviral Vectored Gonadotropin Releasing Hormone Vaccine for Estrus Suppression in Mares 

Jensen, Rochelle (2017-07-27)
The objective of this study was to evaluate an adenoviral vectored gonadotropin releasing hormone (GnRH) vaccine as a method to suppress estrus behavior and cyclicity in mares. An additional objective was to determine the ...

Airway Deposition of Nebulized Voriconazole in Horses 

Sierra Rodriguez, Tamara (2020-11-02)
Voriconazole (VRC) is a potential treatment for pneumomycosis in horses. The objectives of this study were to determine if delivery of Vfend® using a Flexineb® nebulizer produced clinically significant [VRC] in lower ...

Analysis of xenoestrogen effects in the male rat gonad 

Jeminiwa, Bamidele (2021-04-20)  ETD File Embargoed
Naturally occurring estrogenic chemicals existing in food such as soybeans and synthetic xenoestrogens, termed Xenoestrogens, contaminating food and water sources have become issues of public health interest. The concern ...

Angiotensin II-Driven Mechanisms of Neuroinflammation in the Maintenance of Hypertension 

Mowry, Francesca (2021-04-20)
Hypertension, one of the most prevalent cardiovascular risk factors, exhibits numerous pathophysiologies and is typically attributed to dysregulation of the cardiovascular, renal, and/or central nervous systems (CNS). ...

Antimicrobial-resistant bacteria and microbiota identified among flies and their sympatric animals 

Kalalah, Anwar (2020-07-21)  ETD File Embargoed
Antimicrobial resistance is rising globally at an alarming rate as one of the most serious public health challenges. There is increasing evidence that the environment plays a major role in the development and transmission ...

Australian Labradoodle Dystrophinopathy: A Novel Canine Model for the Study of Duchenne Muscular Dystrophy Cardiomyopathy 

Shrader, Stephanie (2020-04-22)
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder that results in progressive damage to both skeletal and cardiac myocytes. As a result of improved ventilatory care, mortality in affected patients is ...

Beneficial Modulation of the Gut Microbiota Prevents Stress-Induced Adverse Effects 

Giblot Ducray, Henri Alexandre (2019-04-18)  ETD File Embargoed
The gut microbiota plays a significant role in maintaining the homeostasis and overall health status of the host. Moreover, it has been shown that heat stress severely alters the stability of the gut microbiota. Thus, ...

A Biodegradable Microparticle Vaccine Platform using Femtomole Peptide Antigen Doses to Elicit T-cell Immunity against Chlamydia abortus 

Chowdhury, Erfan (2016-12-19)
Successful vaccination against Chlamydia spp. has remained elusive, largely due to a lack of vaccine platforms for the required Th1 immunization. Modeling of T helper cell immunity indicates that Th1 immunity requires ...

Biomechanical Testing of Double Hemitenotomy for Equine Deep Digital Flexor Tendon Lengthening 

Zetterström, Sandra (2021-07-14)  ETD File Embargoed
Deep digital flexor (DDF) tenotomy is performed in horses with laminitis to diminish the force of the DDF on the third phalanx (P3) which causes P3 rotation due to loss of laminar integrity counteracting the DDF pull. ...

Canine and Feline Differences in the Cytochrome P450 Transcriptome and Drug Metabolism 

Visser, Marike (2018-04-17)
Cytochrome P450 (CYP) is an important enzyme superfamily, estimated to metabolize 70-90% of pharmaceuticals. Use of pharmaceuticals with at least 30% metabolism by CYP in humans require phenotyping to determine the CYP ...

Cannabinoid: A Potential Anti-Cancer Agent for Non-Hodgkin Lymphoma 

Omer, Saba (2021-07-23)  ETD File Embargoed
The non-Hodgkin lymphomas (NHLs) are a heterogeneous family of lymphoid malignancies and are one of the most commonly diagnosed neoplasm in both dogs and humans. Systemic anticancer chemotherapy is the treatment of choice ...

Cardiac Output Measurements with UDCO and ECHO under general anesthesia during normotension, hypotension and hypertension in adult alpacas 

Diaz Falcon, Noelia (2021-07-30)
Cardiac output (CO) is defined as the quantity of blood pumped into the aorta each minute by the heart. Measurement of CO is considered an important tool to determine oxygen deliver to the tissues. Currently, there are ...

Changes in the Open Reading Frame of Bovine Viral Diarrhea Virus during Serial Infection of Pregnant Cattle, Sheep, and Swine 

Kuca, Thibaud (2018-04-24)
Bovine viral diarrhea virus (BVDV) is an economically important pathogen that is endemic in cattle populations of many countries. This virus can also infect pigs, camelids, and a wide range of ruminants including sheep, ...

Characterization and differentiation of bacteria by hyperspectral analysis 

Riggs, Rebecca (2019-07-19)  ETD File Embargoed
Characterization and differentiation of microorganisms by hyperspectral analysis is a promising alternative to conventional techniques in clinical, food, and environmental microbiology to be used as a rapid, non-destructive ...

Clinical Applications of Therapeutic Drug Monitoring in Canine Idiopathic Epilepsy Patients Receiving Levetiracetam 

Bunn, Haden (2018-11-20)
There are currently no drugs approved for the treatment of canine idiopathic epilepsy and as a result extra-label use of human-approved medications is common. Older agents such as phenobarbital are effective in dogs, but ...

Cloning and characterization of novel ccdc103 interactors 

Daniel, Jeffrey (2020-07-16)  ETD File Embargoed
Coiled-coil domain containing protein 103 is a homodimeric protein that functions as a dynein attachment factor in motile cilia. Ccdc103 defects in zebrafish (Danio rerio) embryos lead to paralyzed motile cilia, pronephric ...

A comparative assessment of phthalate effects on gonadal steroidogenesis in male rats. 

Fischer, John III (2022-05-02)  ETD File Embargoed
Although it is a known endocrine disrupting chemical (EDC) of the male reproductive tract that is ubiquitous in the environment, di (2-ethylhexyl) phthalate (DEHP) has remained the most utilized industrial plasticizer on ...

Comparison of Inflammatory Cell Populations in Young and Mature Beef Bulls; A Preliminary Study 

Rush, Jessica (2019-04-24)
Bovine venereal diseases, such as Tritrichomonas foetus (T. foetus) infection, can be economically devastating to the cattle industry. Decreases in calf crops due to abortion and infertility, premature culling, and loss ...

Comparison of Tensile Strength and Early Healing of Self-Locking and Surgeon’s Knots for Closure of Ventral Midline Celiotomy in Horses 

Weatherall, Kathleen (2020-07-15)
Characteristics of surgical closure are associated with incisional complications. The surgical knot has been shown to be the weakest point of the suture line. Self-locking knots, such as the forwarder (F) and Aberdeen (A) ...

Comparison of the gene encoding the thyroid-stimulating hormone receptor between hyperthyroid and non-hyperthyroid domestic cats. 

Haysom, Laura (2018-07-12)  ETD File Embargoed
The prevalence of feline hyperthyroidism (FH) is increasing, yet the etiology of FH remains to be elucidated. The purpose of this study was to compare exons 1 to 5 of the thyroid-stimulating hormone receptor (TSHR) gene ...